牛樟芝固态发酵产安卓奎诺尔工艺研究  

Optimizing of Technology for Preparation of Antroquinonol from Antrodia cinnamomea by Response Surface Methodology

作　　者：魏海龙[1] 程俊文[1] 胡传久[1] 贺亮[1] 钱华[1] 李海波[1] 王衍彬[1] 邹景泉[1] 蒋云鹤[1] WEI Hai-long;CHENG Jun-wen;HU Chuan-jiu;HE Liang;QIAN Hua;LI Hai-bo;WANG Yan-bin;ZOU Jing-quan;JIANG Yun-he(Key Laboratory of Biological and Chemical Utilization of Forest Resources of Zhejiang, Zhejiang Academy of Forestry, Hangzhou 310023, China)

机构地区：[1]浙江省林业科学研究院浙江省森林资源生物与化学利用重点实验室,浙江杭州310023

出　　处：《浙江林业科技》2017年第4期39-44,共6页Journal of Zhejiang Forestry Science and Technology

基　　金：浙江省科技厅公益技术研究项目(2013C32095);浙江省农业(食用菌)新品种选育重大科技专项(2016C02057-8)

摘　　要：对牛樟芝Antrodia cinnamomea固态发酵生产安卓奎诺尔的工艺条件进行优化。先通过单因素试验,筛选出小麦Triticum aestivum质量、相对湿度、培养温度3个主要影响参数,再应用响应曲面分析法优化。结果表明,牛樟芝产安卓奎诺尔固态发酵最佳条件为:小麦80.82 g,相对湿度58.01%,培养温度28.48℃,安卓奎诺尔的平均产量可达259.79 mg·kg^(-1)。Experiments were conducted on optimizing technology for preparation of antroquinonol from solid-state fermented mycelium of Antrodia cinnamomea.Single factor experiment selected important factors such as mass of Triticum aestivum,relative humidity and culture temperature,and technology was optimized by response factor analysis.The result demonstrated that the average yield of antroquinonol reached259.79mg/kg with wheat of80.82g,relative humidity of58.01%,culture temperature of28.48℃.

关 键 词：牛樟芝 安卓奎诺尔 固体发酵 响应面 

分 类 号：R282.71[医药卫生—中药学]