T-cell/histiocyte-rich large B-cell lymphoma in a child:A case report and review of literature  

作　　者：Chapman Wei Chaplin Wei Omar Alhalabi Lei Chen 

机构地区：[1]George Washington University School of Medicine and Health Sciences at Washington [2]St. George’s University School of Medicine [3]Division of Cancer Medicine,The University of Texas MD Anderson Cancer Center at Houston [4]Department of Pathology and Laboratory Medicine,University of Texas Mc Govern Medical School at Houston

出　　处：《World Journal of Clinical Cases》2018年第6期121-126,共6页世界临床病例杂志

摘　　要：T-cell/histiocyte-rich large B-cell lymphoma is uncommon in children population. There were few cases reported in the literature with wide range clinical presentations including advanced stage, and more involvement of liver, spleen and bone marrow. Head and neck lymphadenopathy tends to present in younger children. We report a case of 10-year-old boy who initially presented intermittent fever, headaches and neck lymphadenopathy. Subsequently, he developed diffuse lymphadenopathy and hepatosplenomegaly. T-cell/histiocyte-rich large B-cell lymphoma was diagnosed on a cervical lymph node biopsy. Cervical lymphadenopathy in this age group is most commonly reactive or nonmalignant processes. Lymphoma is much less frequent; mainly are non-Hodgkin lymphomas. However, a subset of large B-cell lymphoma called T-cell/histiocyte-rich B-cell lymphoma is rare in children.T-cell/histiocyte-rich large B-cell lymphoma is uncommon in children population. There were few cases reported in the literature with wide range clinical presentations including advanced stage, and more involvement of liver, spleen and bone marrow. Head and neck lymphadenopathy tends to present in younger children. We report a case of 10-year-old boy who initially presented intermittent fever, headaches and neck lymphadenopathy. Subsequently, he developed diffuse lymphadenopathy and hepatosplenomegaly. T-cell/histiocyte-rich large B-cell lymphoma was diagnosed on a cervical lymph node biopsy. Cervical lymphadenopathy in this age group is most commonly reactive or nonmalignant processes. Lymphoma is much less frequent; mainly are non-Hodgkin lymphomas. However, a subset of large B-cell lymphoma called T-cell/histiocyte-rich B-cell lymphoma is rare in children.

关 键 词：Pediatric T-cell/histiocyte-rich large B-CELL LYMPHOMA Head and neck LYMPHADENOPATHY 

分 类 号：R[医药卫生]