Autonomic function and ventricular tachyarrhythmias during acute myocardial infarction  

作　　者：Theofilos M Kolettis 

机构地区：[1]Department of Cardiology, Cardiovascular Research Institute and University of Ioannina Medical School

出　　处：《World Journal of Experimental Medicine》2018年第1期8-11,共4页世界实验医学杂志

摘　　要：Most cases of sudden cardiac death are attributed to sustained ventricular tachyarrhythmias(VTs), triggered by acute coronary occlusion. Autonomic dysfunction, an important arrhythmogenic mechanism in this setting, is being actively investigated, aiming at the advent of preventive strategies. Recent experimental studies have shown vagal withdrawal after anterior myocardial infarction, coinciding with high incidence of VTs, followed by more gradual sympathetic activation coinciding with a second arrhythmia peak. This article summarizes recent knowledge on this intriguing topic, generating hypotheses that can be investigated in future experimental and clinical studies.Most cases of sudden cardiac death are attributed to sustained ventricular tachyarrhythmias(VTs), triggered by acute coronary occlusion. Autonomic dysfunction, an important arrhythmogenic mechanism in this setting, is being actively investigated, aiming at the advent of preventive strategies. Recent experimental studies have shown vagal withdrawal after anterior myocardial infarction, coinciding with high incidence of VTs, followed by more gradual sympathetic activation coinciding with a second arrhythmia peak. This article summarizes recent knowledge on this intriguing topic, generating hypotheses that can be investigated in future experimental and clinical studies.

关 键 词：Sudden cardiac death Acute myocardial infarction VENTRICULAR TACHYARRHYTHMIAS VENTRICULAR fibrillation Delayed ARRHYTHMOGENESIS VENTRICULAR TACHYCARDIA Early ARRHYTHMOGENESIS VAGAL ACTIVITY Sympathetic ACTIVITY Arrhythmogenic mechanisms 

分 类 号：R[医药卫生]