Unicentric Castleman's disease associated with end stage renal disease caused by amyloidosis  

作　　者：Eray Eroglu Ismail Kocyigit Aydin Unal Murat Hayri Sipahioglu Hulya Akgun Leylagul Kaynar Bulent Tokgoz Oktay Oymak 

机构地区：[1]Division of Ne-phrology,Department of Internal Medicine,Erciyes University School of Medicine [2]Department of Pathology,Erciyes University School of Medicine [3]Division of Hematology,Department of Internal Medicine,Erciyes University School of Medicine

出　　处：《World Journal of Clinical Cases》2017年第3期119-123,共5页世界临床病例杂志

摘　　要：Castleman's disease(CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lymphadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.Castleman's disease(CD), also known as angiofolicular lymph node hyperplasia, is a rare heterogenous group of lymphoproliferative disorders. Histologically, it can be classified as hyaline vascular type, plasma cell type, or mixed type. Clinically two different subtypes of the CD are present: Unicentric and multicentric. Unicentric CD is generally asymptomatic and associated with hyaline vascular type, and its diagnoses depend on the localized lymphadenopathy on examination or imaging studies. However, multicentric CD presents with generalized lymphadenopathy and systemic symptoms including malaise, fever, night sweats, weight loss, and it is associated with the plasma cell type and mix type. Herein, we report a patient with unicentric CD of the plasma cell type without systemic symptoms, who developed end stage renal failure caused by amyloidosis 6 years after onset of CD.

关 键 词：Castleman’s disease AMYLOIDOSIS Plasma cell INFLAMMATION End stage renal disease 

分 类 号：R597[医药卫生—内科学]