Symptom management during and after treatment with concurrent chemoradiotherapy for oropharyngeal cancer:A review of the literature and areas for future research  

作　　者：Heidi Mason Mary Beth De Rubeis Nancy Burke Melissa Shannon Danielle Karsies Gregory Wolf Avi Eisbruch Francis Worden 

机构地区：[1]University of Michigan School of Nursing

出　　处：《World Journal of Clinical Oncology》2016年第2期220-226,共7页世界临床肿瘤学杂志（英文版）

摘　　要：Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatmentrelated toxicity.Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and disfiguring surgery,treatment related toxicities are often difficult to control.Acute toxicities include mucositis,skin desquamation,depression,cachexia,fatigue and nausea and vomiting.Failure to control these symptoms can adversely affect the patient's ability to complete their treatment regimen.Although there are many promising new treatments in the area of symptom management for this patient population,a review of the literature reflects the need for more research.Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatmentrelated toxicity.Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and disfiguring surgery,treatment related toxicities are often difficult to control.Acute toxicities include mucositis,skin desquamation,depression,cachexia,fatigue and nausea and vomiting.Failure to control these symptoms can adversely affect the patient's ability to complete their treatment regimen.Although there are many promising new treatments in the area of symptom management for this patient population,a review of the literature reflects the need for more research.

关 键 词：Head and neck cancer CHEMORADIOTHERAPY Depression Fatigue CACHEXIA NAUSEA DESQUAMATION MUCOSITIS VOMITING 

分 类 号：R473.73[医药卫生—护理学]