Locoregional treatment of early breast cancer with isolated tumor cells or micrometastases on sentinel lymph node biopsy  

作　　者：Agnès Tallet Eric Lambaudie Monique Cohen Mathieu Minsat Marie Bannier Michel Resbeut Gilles Houvenaeghel 

机构地区：[1]Departement of Radiotherapy,Institut Paoli Calmettes and CRCM [2]Departement of Surgery,Institut Paoli Calmettes and CRCM [3]Aix Marseille Université,Jardin du Pharo

出　　处：《World Journal of Clinical Oncology》2016年第2期243-252,共10页世界临床肿瘤学杂志（英文版）

摘　　要：The advent of sentinel lymph-node technique has led to a shift in lymph-node staging,due to the emergence of new entities namely micrometastases(p N1mi) and isolated tumor cells [p N0(i+)].The prognostic significance of this low positivity in axillary lymph nodes is currently debated,as is,therefore its management.This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting,discussing the locoregional treatment in p N0(i+) and p N1 mi patients(completion axillary dissection,axillary irradiation with or without regional nodes irradiation,or observation),according to systemic treatment,with the goal to help physicians in their daily practice.The advent of sentinel lymph-node technique has led to a shift in lymph-node staging,due to the emergence of new entities namely micrometastases(p N1mi) and isolated tumor cells [p N0(i+)].The prognostic significance of this low positivity in axillary lymph nodes is currently debated,as is,therefore its management.This article provides updates evidence-based medicine data to take into account for treatment decision-making in this setting,discussing the locoregional treatment in p N0(i+) and p N1 mi patients(completion axillary dissection,axillary irradiation with or without regional nodes irradiation,or observation),according to systemic treatment,with the goal to help physicians in their daily practice.

关 键 词：Breast cancer MICROMETASTASES AXILLARY LYMPH node DISSECTION RADIOTHERAPY Isolated tumor cells 

分 类 号：R737.9[医药卫生—肿瘤]