Ins and outs of Helicobacter pylori association with autoimmune rheumatic diseases  

作　　者：Jibran Sualeh Muhammad Syed Faisal Zaidi Muhammad Ishaq 

机构地区：[1]Department of Gastroenterology and Hematology,Faculty of Medicine,University of Toyama [2]Department of Basic Medical Sciences,College of Medicine,King Saud bin Abdulaziz University of Health Sciences [3]Department of Internal Medicine,Jinnah Medical College Hospital

出　　处：《World Journal of Rheumatology》2015年第2期96-100,共5页世界风湿病学杂志

摘　　要：Helicobacter pylori(H.pylori) infection is widely prevalent throughout worldwide.H.pylori manage a long-term survival in hostile environment of human stomach leading to peptic ulcer diseases and gastric cancer.But mostly infected person remains asymptomatic.Its chronic interaction with immune system makes H.pylori as an attractive candidate for the researchers to study its association with autoimmune diseases.This article presents a review of the literature on the association of H.pylori infection in selective autoimmune rheumatic diseases(RD).The authors used Me SH terms "Helicobacter pylori " with "rheumatoid arthritis," "systemic lupus erythematosus," or "fibromyalgia" to search Pub Med database.All relevant studies identified were included.Despite extensive medical advancement many questions on role of H.pylori infection in autoimmune RD still remain unanswered.Further studies are therefore needed to address the role of H.pylori in pathogenesis of RD.Helicobacter pylori(H.pylori) infection is widely prevalent throughout worldwide.H.pylori manage a long-term survival in hostile environment of human stomach leading to peptic ulcer diseases and gastric cancer.But mostly infected person remains asymptomatic.Its chronic interaction with immune system makes H.pylori as an attractive candidate for the researchers to study its association with autoimmune diseases.This article presents a review of the literature on the association of H.pylori infection in selective autoimmune rheumatic diseases(RD).The authors used Me SH terms "Helicobacter pylori " with "rheumatoid arthritis," "systemic lupus erythematosus," or "fibromyalgia" to search Pub Med database.All relevant studies identified were included.Despite extensive medical advancement many questions on role of H.pylori infection in autoimmune RD still remain unanswered.Further studies are therefore needed to address the role of H.pylori in pathogenesis of RD.

关 键 词：AUTOIMMUNITY Systemic lupus ERYTHEMATOSUS RHEUMATOID arthritis FIBROMYALGIA HELICOBACTER PYLORI 

分 类 号：R[医药卫生]