Intra-abdominal desmoid tumor after liver transplantation: A case report  

作　　者：Vidya A Fleetwood Shannon Zielsdorf Sheila Eswaran Shriram Jakate Edie Y Chan 

机构地区：[1]Department of General Surgery,Division of Transplantation Surgery,Rush University Medical Center,Chicago,IL 60612,United States [2]Department of Medicine,Section of Hepatol-ogy,Rush University Medical Center,Chicago,IL 60612,United States [3]Department of Pathology,Rush University Medical Center,Chicago,IL 60612,United States

出　　处：《World Journal of Transplantation》2014年第2期148-152,共5页世界移植杂志

摘　　要：We are reporting the first documented case of an abdominal desmoid tumor presenting primarily after liver transplantation. This tumor, well described in the literature as occurring both in conjunction with familial adenomatous polyposis as well as in the postsurgical patient, has never been noted after solid organ transplantation and was therefore not included in our differential upon presentation. Definitive diagnosis required the patient to undergo surgical excision and immunochemical staining of the mass for confirmation. A review of the literature showed no primary tumors after transplantation. In a population of patients who received a small bowel transplant after they developedshort gut post radical resection of aggressive fibromatosis, only rare recurrences were seen. No connection of tumor development with immunosuppression or need to decrease immunosuppressant treatment has been demonstrated in these patients. Our case and the literature show the risk of this tumor presenting in the post-transplantation patient and the need for a high index of suspicion in patients who present with a complex mass after transplantation to prevent progression of the disease beyond a resectable lesion. Results of a thorough search of the literature are detailed and the medical and surgical management of both resectable and unresectable lesions is reviewed.We are reporting the first documented case of an abdominal desmoid tumor presenting primarily after liver transplantation. This tumor, well described in the literature as occurring both in conjunction with familial adenomatous polyposis as well as in the postsurgical patient, has never been noted after solid organ transplantation and was therefore not included in our differential upon presentation. Definitive diagnosis required the patient to undergo surgical excision and immunochemical staining of the mass for confirmation. A review of the literature showed no primary tumors after transplantation. In a population of patients who received a small bowel transplant after they developedshort gut post radical resection of aggressive fibromatosis, only rare recurrences were seen. No connection of tumor development with immunosuppression or need to decrease immunosuppressant treatment has been demonstrated in these patients. Our case and the literature show the risk of this tumor presenting in the post-transplantation patient and the need for a high index of suspicion in patients who present with a complex mass after transplantation to prevent progression of the disease beyond a resectable lesion. Results of a thorough search of the literature are detailed and the medical and surgical management of both resectable and unresectable lesions is reviewed.

关 键 词：DESMOID INTRA-ABDOMINAL FIBROMATOSIS IMMUNOSUPPRESSION Liver TRANSPLANTATION Solid ORGAN TRANSPLANTATION Recurrence 

分 类 号：R[医药卫生]