Hand bone mass in rheumatoid arthritis:A review of the literature  

作　　者：Gamze Kilic Salih Ozgocmen 

机构地区：[1]Division of Rheumatology,Department of Physical Medicine and Rehabilitation,Erciyes University,School of Medicine,Gevher Nesibe Hospital

出　　处：《World Journal of Orthopedics》2015年第1期106-116,共11页世界骨科杂志（英文版）

摘　　要：Rheumatoid arthritis(RA) is a common chronic inflammatory disease and periarticular osteoporosis or osteopenia of the inflamed hand joints is an early feature of RA Quantitative measurement of hand bone loss may be an outcome measure for the detection of joint destruction and disease progression in early RA. This systematic review examines the published literature reporting hand bone mass in patients with RA, particularly those using the dual X-ray absorptiometry(DXA) methods The majority of the studies reported that hand bone loss is associated with disease activity, functional statusand radiological progression in early RA. Quantitative measurement of hand bone mineral density by DXA may be a useful and practical outcome measure in RA and may be predictive for radiographic progression or functional status in patients with early RA.Rheumatoid arthritis(RA) is a common chronic inflammatory disease and periarticular osteoporosis or osteopenia of the inflamed hand joints is an early feature of RA Quantitative measurement of hand bone loss may be an outcome measure for the detection of joint destruction and disease progression in early RA. This systematic review examines the published literature reporting hand bone mass in patients with RA, particularly those using the dual X-ray absorptiometry(DXA) methods The majority of the studies reported that hand bone loss is associated with disease activity, functional statusand radiological progression in early RA. Quantitative measurement of hand bone mineral density by DXA may be a useful and practical outcome measure in RA and may be predictive for radiographic progression or functional status in patients with early RA.

关 键 词：RHEUMATOID ARTHRITIS HAND bone density Dual X-ray ABSORPTIOMETRY PERIARTICULAR Osteoporosis 

分 类 号：R593.22[医药卫生—内科学]