应用新型超声诊断仪检测大鼠心功能  

Detection of cardiac functions in rats using a new ultrasonic diagnostic apparatus

作　　者：陈婷婷[1] 廖献杉 曾兰 梁榜辉 杨楚仪 吴莹 李璇 欧阳轶强 何萍 黄勤[1] CHEN Tingting;LIAO Xianshan;ZENG Lan;LIANG Banghui;YANG Chuyi;WU Ying;LI Xuan;OUYANG Yiqiang;HE Ping;HUANG Qin(Basic Medical School,Guangxi Medical University,Nanning 530021,China;Department of Ultrasound,the First Affiliated Hospital of Guangxi Medical University,Nanning 530021;Experimental Animal Center of Guangxi Medical University,Nanning 530021)

机构地区：[1]广西医科大学基础医学院,南宁530021 [2]广西医科大学第一附属医院超声科,南宁530021 [3]广西医科大学实验动物中心,南宁530021

出　　处：《中国比较医学杂志》2018年第11期106-110,共5页Chinese Journal of Comparative Medicine

基　　金：国家自然科学基金地区基金项目(81660360)

摘　　要：目的应用一种新型超声诊断仪,通过二维和M型超声心动图评估大鼠心功能,了解该方法的可行性及准确性。方法应用该新型超声诊断仪,探头频率为6 MHz～19 MHz,对6只正常雄性SD大鼠麻醉后经胸超声检测左室结构及各项指标。结果经胸超声心动图能够清楚地显示大鼠心脏大体结构,并且可以准确稳定地获得大鼠左心室各项心功能参数,可用于评价大鼠心功能。结论使用该新型超声诊断仪可获得高质量的大鼠心脏大体结构图像和稳定可靠的心功能数据,是一种可以连续地、准确地检查大鼠心脏大体结构和评价心功能的无创方法。Objective A new type of ultrasonic diagnostic apparatus was used to evaluate the cardiac functions of rats by two-dimensional and M-mode echocardiography,and the feasibility and accuracy of this method were assessed.Methods A new type of ultrasonic diagnostic apparatus with a probe frequency of 6 MHz-19 MHz was applied.The left ventricular structure and various indexes were detected by transthoracic ultrasound after anesthesia in six normal male SD rats.Results Transthoracic echocardiography clearly showed the general structure of the rat heart,and accurately and stably obtained the cardiac function parameters of the left ventricle of rats,which can be used to evaluate the cardiac functions of rats.Conclusions High-quality rat cardiac gross structural images,and stable and reliable cardiac function data can be obtained using this new ultrasonic diagnostic apparatus.It is a non-invasive method for continuously and accurately examining the gross structure of the rat heart and evaluating the cardiac functions.

关 键 词：超声心动图 新型超声仪 大鼠 心功能 

分 类 号：R-33[医药卫生]