表没食子儿茶素没食子酸酯(EGCG)抗氧化作用在眼科研究中的应用  

Research advance of the mechanism of epigallocatechingallate against oxidative damage in ophthalmology

作　　者：吴秋欣[1] 王慧[2] 刘冬梅[1] 毕宏生[1] WU Qiu-Xin;WANG Hui;LIU Dong-Mei;BI Hong-Sheng(Affiliated Eye Hospital of Shandong University of Traditional Chinese Medicine,Shandong Provincial Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases,Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Therapy of Ocular Diseases in Universities of Shandong,Jinan 250002,Shandong Province,China;Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong Province,China)

机构地区：[1]山东中医药大学附属眼科医院,山东省中西医结合眼病防治重点实验室,山东省高校中西医结合眼病防治技术(强化)重点实验室,山东省济南市250002 [2]山东中医药大学,山东省济南市250014

出　　处：《眼科新进展》2019年第3期287-290,共4页Recent Advances in Ophthalmology

基　　金：山东省自然科学基金项目(编号:ZR2017PH002;ZR2014H-048)~~

摘　　要：表没食子儿茶素没食子酸酯(epigallocatechingallate,EGCG)为绿茶提取物茶多酚的有效成分,具有非常强的抗氧化活性,近年来EGCG得到广泛的研究。研究表明,EGCG可以通过抗氧化作用抑制细胞凋亡,从而保护细胞,减少氧化损伤。近年来一些学者专注于EGCG对眼科疾病防治的研究。本文就EGCG抗氧化作用在眼科的应用进行综述。Epigallocatechingallate (EGCG) is an effective component of tea polyphenols from green tea extract,which possesses very strong antioxidant activity.In the past few years,EGCG has been widely studied for its antioxidant activity.Studies have shown that EGCG can inhibit cell apoptosis through anti-oxidation pathways,thereby protecting cells from oxidative damage.Some scholars have focused on EGCG research on the prevention and control of eye diseases.In the present paper,we reviewed the application of EGCG in ophthalmology.

关 键 词：表没食子儿茶素没食子酸酯 抗氧化作用 眼科 

分 类 号：R776.1[医药卫生—眼科]