基于双频微波固态源的热消融系统设计研究  

Design and Research of Thermal Ablation System Based on Dual-frequency Microwave Solid State Source

作　　者：沐勇杰 王娟[1] 赵金哲[1] 晋晓飞 钱志余[1] MU Yongjie;WANG Juan;ZHAO Jinzhe;JIN Xiaofei;QIAN Zhiyu(School of Nanjing University of Aeronautics and Astronautics,Nanjing,210016)

机构地区：[1]南京航空航天大学

出　　处：《中国医疗器械杂志》2019年第3期173-175,201,共4页Chinese Journal of Medical Instrumentation

基　　金：自然科学基金国家重大科研仪器研制项目(81827803,81727804);江苏省自然科学基金(BK20160814);江苏省社会发展计划(BE2016759);南京航空航天大学研究生创新基地(实验室)开放基金(kfjj20180304)

摘　　要：微波热消融技术以其微创、副作用小的优点被广泛应用于肝肿瘤的治疗。热剂量的精准控制在很大程度上决定了微波热消融的治疗效果。然而,目前基于磁控管的微波热消融仪具有功率输出稳定性欠佳、工作电压较高的缺点。针对以上问题,该文选择微波固态源作为微波输出的核心器件,设计了一套基于2450MHz和433MHz的双频微波热消融系统,系统利用功率检测电路对系统实际输出功率进行PID反馈控制。实验结果表明系统输出功率最大误差小于1W,PID算法在提高系统安全性的同时进一步增强了系统输出功率的准确性与稳定性。该文设计的双频微波热消融系统可以为后续的研究提供一个安全可靠的实验平台。Microwave thermal ablation technology is widely used in the treatment of liver tumors because of its minimal invasiveness and small side effects.The precise control of the thermal dose largely determines the therapeutic effect of microwave thermal ablation.However,the current magnetron-based microwave thermal ablation device has the disadvantages of poor power output stability and high operating voltage.In view of the above problems,this paper selected the microwave solid-state source as the core device of microwave output,and designed a dual-frequency microwave thermal ablation system based on 2 450 MHz and 433 MHz.The system used the power detection circuit to perform PID feedback control on the actual output power of the system.The experimental results show that the maximum output power of the system is less than 1 W.The PID algorithm further enhances the accuracy and stability of the system output power while improving the system security.The dual-frequency microwave thermal ablation system designed in this paper can provide a safe and reliable experimental platform for subsequent research.

关 键 词：微波热消融 肝肿瘤 热剂量 微波固态源 PID算法 

分 类 号：R735.7[医药卫生—肿瘤] R197.39[医药卫生—临床医学]