Stereotactic body radiation therapy in patients with hepatocellular carcinoma: A mini-review  

作　　者：Sabine Gerum Alexandra D Jensen Falk Roeder 

机构地区：[1]Department of Radiation Oncology, University Hospital LMU Munich [2]Department of Radiation Oncology, University Hospital Gie?en and Marburg [3]CCU Molecular Radiation Oncology, German Cancer Research Center [4]Department of Radiotherapy and Radiation Oncology, Paracelsus Medical University

出　　处：《World Journal of Gastrointestinal Oncology》2019年第5期367-376,共10页世界胃肠肿瘤学杂志（英文版）（电子版）

摘　　要：Stereotactic body radiation therapy(SBRT) is an emerging treatment for hepatocellular carcinoma. This technique results in excellent local control rates with favorable toxicity profile despite being predominantly used in heavily pretreated patients or those unsuitable for other local therapies. SBRT may be used as a sole treatment or in combination with other local therapies as well as a bridging strategy for patient awaiting liver transplants. This brief review describes current practice of SBRT with respect to radiation technique, patient selection and treatment concepts. It summarizes available evidence from retroand prospective studies evaluating SBRT alone, SBRT in combination with other treatments and SBRT compared to other local treatment approaches.Stereotactic body radiation therapy(SBRT) is an emerging treatment for hepatocellular carcinoma. This technique results in excellent local control rates with favorable toxicity profile despite being predominantly used in heavily pretreated patients or those unsuitable for other local therapies. SBRT may be used as a sole treatment or in combination with other local therapies as well as a bridging strategy for patient awaiting liver transplants. This brief review describes current practice of SBRT with respect to radiation technique, patient selection and treatment concepts. It summarizes available evidence from retroand prospective studies evaluating SBRT alone, SBRT in combination with other treatments and SBRT compared to other local treatment approaches.

关 键 词：HEPATOCELLULAR CARCINOMA STEREOTACTIC body radiation therapy Local-ablative treatment Combination approaches Mini-review 

分 类 号：R[医药卫生]