Targeted neuromodulation of abnormal interhemispheric connectivity to promote neural plasticity and recovery of arm function after stroke: a randomized crossover clinical trial study protocol  

作　　者：Borich MR Wolf SL Tan AQ 

机构地区：[1]不详

出　　处：《中华物理医学与康复杂志》2019年第5期343-343,共1页Chinese Journal of Physical Medicine and Rehabilitation

摘　　要：BACKGROUND AND OBJECTIVE Despite intensive rehabilitation efforts, most stroke survivors have persistent functional disability of the paretic arm and hand. These motor impairments may be due in part to maladaptive changes in structural and functional connections between brain regions. The following early stage clinical trial study protocol describes a noninvasive brain stimulation approach to target transcallosally mediated interhemispheric connections between the ipsi- and contralesional motor cortices (iM1 and cM1) using corticocortical paired associative stimulation (ihPAS). This clinical trial aims to characterize ihPAS-induced modulation of interhemispheric connectivity and the effect on motor skill performance and learning in chronic stroke survivors.

关 键 词：PROMOTE neural plasticity FUNCTION AFTER STROKE ihPAS 

分 类 号：R[医药卫生]