血清高半胱氨酸与脑小血管病  

Serum homocysteine and cerebral small vessel diseases

作　　者：王佳莹 慕经纬 蔺慕会[2] 陈晓虹[2] Wang Jiaying;Mu Jingwei;Lin Muhui;Chen Xiaohong(China Medical University,Shenyang 110122,China;Department of Neurology,Liaoning Province People's Hospital,Shenyang 110016,China)

机构地区：[1]中国医科大学,沈阳110122 [2]辽宁省人民医院神经内科,沈阳110016

出　　处：《国际脑血管病杂志》2019年第4期280-286,共7页International Journal of Cerebrovascular Diseases

基　　金：辽宁省自然科学基金(20170540528).

摘　　要：高半胱氨酸(homocysteine,Hcy)是一种含硫的蛋氨酸代谢中间产物,正常情况下在血液中处于较低的水平。近年的研究表明,血清Hcy水平升高是缺血性卒中的独立危险因素,并可增高脑小血管病(cerebral small vessel disease,CSVD)的风险。文章对Hcy与CSVD的关系进行了综述。Homocysteine (Hcy) is a sulfur-containing metabolic intermediate of methionine, which is normally at a lower level in the blood. Recent studies have shown that the elevated blood level of Hcy is an independent risk factor for ischemic stroke and increases the risk of occurrence of cerebral small vessel disease (CSVD). This article reviews the relationship between Hcy and CSCD.

关 键 词：脑小血管疾病 高半胱氨酸 高同种半胱氨酸血症 生物标志物 危险因素 

分 类 号：R743[医药卫生—神经病学与精神病学]