孕妇对无创产前检测的认知、态度、意愿及需求调查  

Survey on cognition,attitude,willingness and demand for non-invasive prenatal testing among pregnant women

作　　者：玛尔孜娅·玉苏甫江 罗飞 刘宇[2,3] 董媛媛 徐刚[1] 周欣怡[1] 金萍 李娜[1] Maerziya YUSUFUJIANG;LUO Fei;LIU Yu;DONG Yuan-yuan;XU Gang;ZHOU Xin-yi;JIN Ping;LI Na(Shanghai Jiao Tong University School of Public Health,Shanghai 200025,China;Department of Pediatric Endocrinology/Genetics,Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200092,China;Shanghai Institute for Pediatric Research,Shanghai 200092,China)

机构地区：[1]上海交通大学公共卫生学院,上海200025 [2]上海交通大学医学院附属新华医院小儿内分泌/遗传科,上海200092 [3]上海市儿科医学研究所,上海200092

出　　处：《上海交通大学学报（医学版）》2019年第6期648-654,648,共7页Journal of Shanghai Jiao tong University:Medical Science

基　　金：上海交通大学公共卫生学院卓越公共卫生人才培养项目;上海交通大学医学院地方高水平大学成果为导向本科生拔尖培养项目~~

摘　　要：目的·了解孕妇对无创产前检测技术的认知程度、态度、意愿和需求。方法·选择上海交通大学医学院附属新华医院318名血清学唐氏综合征筛查低风险孕妇及534名在上海多家医院经血清学唐氏综合征筛查发现为高风险并前往上海交通大学医学院附属新华医院无创产前检测门诊的孕妇作为研究对象。就852名孕妇对无创产前检测技术的认知程度、态度、意愿和需求进行问卷调查。结果·回收问卷760份,其中有效问卷共728份,有效问卷率为85.45%。孕妇对无创产前检测的认知达标率仅为51.24%,但83.10%的孕妇对无创产前检测的推广持积极态度。79.54%的孕妇认为在无创产前检测前提供的遗传咨询非常必要。结论·加强产前健康宣传教育、做好无创产前检测前的遗传咨询,可提高孕妇的认知程度,有助于合理利用无创产前检测。Objective To understand the cognition,attitude,willingness and demand for non-invasive prenatal testing (NIPT) of pregnant women.Methods A total of 852 pregnant women were enrolled,including 318 pregnant women with low risk of Down syndrome screened in Xinhua Hospital,Shanghai Jiao Tong University School of Medicine,and 534 pregnant women with high risk of Down syndrome screened in several hospitals in Shanghai who further went to Xinhua Hospital,Shanghai Jiao Tong University School of Medicine for NIPT to confirm the diagnosis of Down syndrome screening.The information about the cognition,attitude,willingness and demand for NIPT was collected by a standard questionnaire.Results A total of 760 questionnaires were collected,of which 728 ones were valid,with an effective questionnaire rate of 85.45%.The proportion of pregnant women with ideal cognition level was 51.24%.However,83.10% of pregnant women held a positive attitude towards the promotion of NIPT.There were 79.54% of pregnant women considering it necessary to provide genetic counseling before NIPT.Conclusion It is of great significance to strengthen the prenatal propaganda and education and pre-test genetic counseling so as to improve the cognitive level of pregnant women and make rational use of NIPT.

关 键 词：无创产前检测 产前筛查 产前诊断 孕妇 

分 类 号：R714.55[医药卫生—妇产科学]