后巩膜加固术控制青少年高度近视发展的Meta分析  

The efficacy and safety of posterior scleral reinforcement for high myopia in children:A Meta-analysis

作　　者：高锦展 何利[1] 陈梦平[1] 王素萍[1] Gao Jinzhan;He Li;Chen Meng-ping(Department of Ophthalmology,Zhengzhou Second Hospital,Zhengzhou 450000,China)

机构地区：[1]郑州市第二人民医院眼科

出　　处：《中国斜视与小儿眼科杂志》2019年第2期26-27,I0003,I0004,共4页Chinese Journal of Strabismus & Pediatric Ophthalmology

摘　　要：目的研究后巩膜加固术对青少年进展性高度近视进展控制的疗效与安全性。方法全面检索美国国立医学图书馆(PubMed)、Cochrane循证医学数据库(Cochrane Library)、中国知网CNKI、万方数据库、维普数据库。获取后巩膜加固术控制高度近视进展的文献,按照风险偏倚评估工具对获取文献进行风险偏倚评估。疗效结局指标为末诊裸眼视力(UCVA)、最佳矫正视力(BCVA)、眼轴长度(AL)、等效球镜度(SE)及眼压(IOP)升高发生率。连续变量计量资料运用均数差(MD)作为合并效应量,二分类变量以比值比(OR)为疗效分析统计量,运用Cochrane协作网的Revman5.2软件统计学分析。结果本研究共纳入5篇文献。PSR组及对照组末诊UCVA、AL及SE有统计学差异[MD(UCVA)=0.04,95%CI为(0.02,0.05);MD(AL)=-0.43,95%CI为(-0.57,-0.30);MD(SE)=1.05,95%CI为(0.67,1.43)]。PSR组及对照组末诊BCVA无统计学差异[MD=0.06,95%CI为(-0.02,0.13)]。结论后巩膜加固术能够控制高度近视的发展,稳定眼轴及屈光度。Objective Evaluate the efficacy and safety of the posterior scleral reinforcement for the progressing of high myopia in children or teenagers.Method Using databases of Pub Med,Cochrane Library,CNKI,WanFang Data,CQVIP,searching the papers about the trials on the posterior scleral reinforcement for high myopia.Based on the assessing risk of bias tool,the enrolled articles are assessed for the risk of bias.The compared endpoint outcome indexes are uncorrected visual acuity(UCVA),best-corrected visual acuity(BCVA),axial length(AL),spherical equivalent(SE),rate of higher Intraocular pressure(IOP).Continuous variables use mean difference(MD)as the combined effect size,two categorical variables use odds ratio(OR)for the efficacy analysis statistics.Results 5 articles were enrolled in this study.There is obvious different statistically in UCVA,AL and SE between PSR group and control group at the end visit,while not the BCVA.Conclusion The posterior scleral reinforcement surgery is effective in controlling the progressing of high myopia in children or teenagers.

关 键 词：后巩膜加固术 青少年 高度近视 病理性近视 META分析 

分 类 号：R778.11[医药卫生—眼科]