The Effects of Vitamin D and Calcium levels On Pregnant Women with Hyperemesis Gravidarum: Cross-Sectional Study  

作　　者：Noor J. Al-Saigh Aliaa Al-Safi Hussam W. Al-Humadi Rafal Al-Saigh 

机构地区：[1]Kerbala Health Office,Minstry of Health,Iraq [2]Department of Community Medicine,College of Medicine,Baghdad University,Iraq [3]Department of Clinical Pharmacy,Dean of College of Pharmacy,University of Babylon,Iraq [4]Department of Clinical Laboratory Sciences,College of Pharmacy,University of Babylon,Iraq

出　　处：《Journal of Medicines Development Sciences》2018年第1期31-39,共9页药物发展科学期刊

摘　　要：Background: Vitamin D (VD) deficiency and serum calcium level has undefined relation with hyperemesis gravidarum (HG) during pregnancy.The present study objective was to investigate the levels of VD and calcium in pregnant women with HG and their effects on their obstetric health.Methods: This is a cross-sectional study including 97 pregnant participants with HG.The demographic data including previous and current obstetrical history and body mass index were collected by well-trained researcher following structured questionnaire after obtaining their verbal consent.Laboratory Investigations were done with estimation of VD and calcium.Results: The deficient VD among participant was 84% and low calcium was 54%.There was no significant difference with high correlation between women with low VD and those with normal regarding status of pregnancy and regarding anemia and dietary history (r2=1.0).On the other hand,there was no significant difference with weak correlation between women with low VD and calcium regarding the parity (VD:r2=0.46;calcium:r2=0.03).Moreover,women with normal VD and calcium were less likely to report a history of miscarriage.Conclusion: There was relationship between VD deficiency and HG with low calcium that might be associated with the insignificantly increasing the complication of pregnancy like miscarriage and fetal death.Furthermore,pre-pregnancy dietary intake might influence the severity of HG during following pregnancy.

关 键 词：VITAMIN D CALCIUM PREGNANCY HYPEREMESIS gravidarum 

分 类 号：R[医药卫生]