Olea europaea leaves delay the onset of toxicity of Cerastes cerastes venom in male Swiss albino mice  

作　　者：Inass A Al sadawia Alla M. Hashkela Halima A. Gbaj Asia Mohameda Nesren M. Magela Salah M. Bensabera Fathi M Sherifb Massaud Salem Maamarc Nahed M Almakid Anton Hermanne Abdul M. Gbaja 

机构地区：[1]Department of Medicinal Chemistry,Faculty of Pharmacy,University of Tripoli,M16. [2]Department of Pharmacology,Faculty of Pharmacy,University of Tripoli,M16,Libya. [3]Zoology Department,Faculty of Science,Tripoli University [4]Tripoli Central Hospital,Tripoli,Libya. [5]Department of Biosciences,University of Salzburg,Salzburg,A-5020,Austria

出　　处：《Journal of Medicines Development Sciences》2018年第1期58-62,共5页药物发展科学期刊

摘　　要：We investigated the anti-Cerastes cerastes venom effect of aqueous olive leaf extract.The mitigation in the mean survival time of the albino mice were used to deduce the antivenom property of this extract after challenging with LD99 of snake venom.The aqueous extract of olive leaf significantly increases the mean survival time and the protection fold,but could not protect animals from death when used alone.The higher dose,i.e.,33 g/kg was found better than that of the lower dose of 15 g/kg.The anti-snake venom was found to be more efficient than the aqueous olive leaf extract.

关 键 词：Cerastes cerastes anti-snake VENOM aqueous OLIVE LEAF extract 

分 类 号：R[医药卫生]