UIM-UDS: a new interface between ATG8 and its interactors  

作　　者：Yuchen Lei Daniel J. Klionsky 

机构地区：[1]Life Sciences Institute and Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA

出　　处：《Cell Research》2019年第7期507-508,共2页细胞研究（英文版）

摘　　要：The autophagy-related protein ATG8 (mammalian LC3) plays a key role in cargo recognition during selective macroautophagy/autophagy. The ubiquitin-interacting motif (UIM)-UIM-docking site (UDS) was recently identified as a new interface between ATG8 and its interactors, which expands the list of autophagy receptors and adaptors, and also suggests an additional avenue for potential therapeutic designs for the treatment of human diseases.

关 键 词：ATG8 ROLE DISEASES 

分 类 号：Q[生物学]