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Role of mitophagy in spinal cord ischemia-reperfusion injury
《Neural Regeneration Research》2026年第2期598-611,共14页Yanni Duan Fengguang Yang Yibao Zhang Mingtao Zhang Yujun Shi Yun Lang Hongli Sun Xin Wang Hongyun Jin Xuewen Kang 
supported by Cuiying Scientific and Technological Innovation Program of Second Hospital of Lanzhou University,Nos.CY2023-QN-B18(to YD),2020QN-16(to YZ);the Natural Science Foundation of Gansu Province,No.22JR11RA082(to YZ);Key R&D Plan of Gansu Provincial Department of Science and Technology-Social Development Projects,No.23YFFA0043(to XK).
Spinal cord ischemia-reperfusion injury,a severe form of spinal cord damage,can lead to sensory and motor dysfunction.This injury often occurs after traumatic events,spinal cord surgeries,or thoracoabdominal aortic su...
关键词：BNIP3 BNIP3L/NIX FUNDC1 mechanism MITOCHONDRIA MITOPHAGY modulators PARKIN PINK1 spinal cord ischemia-reperfusion injury 
Novel insights into non-coding RNAs and their role in hydrocephalus
《Neural Regeneration Research》2026年第2期636-647,共12页Zhiyue Cui Jian He An Li Junqiang Wang Yijian Yang Kaiyue Wang Zhikun Liu Qian Ouyang Zhangjie Su Pingsheng Hu Gelei Xiao 
supported by the National Natural Science Foundation of China,Nos.82171347,82371362;the Natural Science Foundation of Hunan Province,No.2022JJ30971;the Scientific Research Project of Hunan Provincial Health Commission of China,No.202204040024(all to GX).
A large body of evidence has highlighted the role of non-coding RNAs in neurodevelopment and neuroinflammation.This evidence has led to increasing speculation that non-coding RNAs may be involved in the pathophysiolog...
关键词：HYDROCEPHALUS NEURODEVELOPMENT NEUROINFLAMMATION non-coding RNA therapeutic target 
Neuronal plasticity and its role in Alzheimer's disease and Parkinson's disease
《Neural Regeneration Research》2026年第1期107-125,共19页Israt Jahan Mohammad Harun-Ur-Rashid MdAminul Islam Farhana Sharmin Soad K.Al Jaouni Abdullah M.Kaki Samy Selim 
financially supported by King Abdulaziz University,Deanship of Scientific Research(DSR)。
Neuronal plasticity,the brain's ability to adapt structurally and functionally,is essential for learning,memory,and recovery from injuries.In neurodegenerative diseases such as Alzheimer's disease and Parkinson's dise...
关键词：Alzheimer's disease long-term depression long-term potentiation NEUROINFLAMMATION neuronal plasticity Parkinson's disease synaptic plasticity 
Alzheimer's disease and the immune system:the emerging role of TEMRA cells
《Neural Regeneration Research》2025年第12期3529-3530,共2页Edric D.Winford Adam D.Bachstetter 
Alzheimer's disease (AD) is the most common form of dementia,affecting millions worldwide.It is cha racterized by progressive cognitive decline and changes in behavior and personality,attributed to neuropathological c...
关键词：ALZHEIMER AΒ TAU 
Role of resident memory T cells in neuroinflammatory and neurodegenerative diseases in the central nervous system
《Neural Regeneration Research》2025年第11期3227-3228,共2页Kimitoshi Kimura 
The immune system has been attracting increasing attention in the field of chronic neurological disorders in the central nervous system(CNS).Autoreactive T cells targeting CNS antigens play a crucial role in the devel...
关键词：DISEASES DEGENERATIVE PATHOLOGY 
Gut virome and its emerging role in inflammatory bowel disease
《World Journal of Methodology》2025年第3期22-24,共3页Rahat Khatoon Khokhar Abdulqadir J Nashwan 
Inflammatory bowel disease(IBD)is a progressive multifactorial inflammatory disease of the gut.The cause of IBD is yet unknown.Some researchers have shown that genetic factors,environmental factors,and the gut microbi...
关键词：Inflammatory bowel disease PATHOGENESIS Gut virome BACTERIOPHAGE Eukaryotic viruses 
Inquiry of modulatory role of sea buckthorn fruit oil on dyslipidemia and gut microbiota in hyperlipidemia mice
《Food Science and Human Wellness》2025年第4期1529-1537,共9页Pimiao Huang Zehua Chen Wenzi Li Aihua Su Chun Cui 
supported by the National Natural Science Foundation of China(31201416);Programme of Introducing Talents of Discipline to Universities(B17018)。
Hyperlipidemia constitutes a critical factor in the pathogenesis of vascular disease and gut microbiota dysbiosis.This study aims to investigate the role of sea buckthorn fruit oil(SBFO)in ameliorating hyperlipidemia,...
关键词：Sea buckthorn fruit oil HYPERLIPIDEMIA Gut microbiota Molecular mechanism 
Role of glutathione transferase in phase separation of FUS and TAF15 in neurons
《Neural Regeneration Research》2025年第7期1999-2000,共2页Kiyoung Kim 
supported by the BK21 FOUR(Fostering Outstanding Universities for Research)and the Basic Science Research Program through the National Research Foundation of Korea(NRF),funded by the Ministry of Education(MOE)and the Ministry of Science and ICT(MSIT)(NRF-2022R1A2C1004204,RS-2023-00219563,2023-DD-UP-0007);by the Soonchunhyang University Research Fund(to KK)。
Amyotrophic lateral sclerosis(ALS)is a progressive neurodegenerative disorder characterized by the degeneration of motor neurons in the brain and spinal cord,leading to muscle weakness,paralysis,and ultimately death(C...
关键词：DEGENERATION FUS AGGREGATION 
Immunohistochemical expression of matrix metalloproteinase-9 and 13 in oral squamous cell carcinoma and their role in predicting lymph node metastasis
《World Journal of Methodology》2025年第2期108-116,共9页Bhari Sharanesha Manjunatha Keshav T Handge Vandana Sandeep Shah Yasser Eid Al-Thobaiti Deepak Gowda Sadashivappa Pateel 
BACKGROUND One of the main characteristics of oral squamous cell carcinoma(OSCC)is that it metastasizes to cervical lymph nodes frequently with a high degree of local invasiveness.A primary feature of malignant tumors...
关键词：Matrix metalloproteinases Oral squamous cell carcinoma Tumor staging IMMUNOHISTOCHEMISTRY INVASION Lymph node metastasis TNM stage 
The multifaceted role of post-translational modifications of LSD1 in cellular processes and disease pathogenesis
《Genes & Diseases》2025年第3期168-179,共12页Yinrui Li Bo Wang Yichao Zheng Huiqin Kang Ang He Lijuan Zhao Ningjie Guo Hongmin Liu Adil Mardinoglu M.A.A.Mamun Ya Gao Xiaobing Chen 
supported by the Basic Research of Medical Science and Technique Foundation of Henan Province,China(No.SBGJ202301004 to X.B.C.);the Key Project of the High Education from the Education Department of Henan Province,China(No.22ZX008 to Y.C.Z.);the Youth Supporting Program from Henan Province,China(No.2021HYTP060 to Y.C.Z.);the Youth Supporting Program from Zhengzhou University(No.JC202044046 to Y.C.Z.);the Science and Technology Project of Henan Province,China(No.232102311179 to Y.G.);the National Natural Science Foundation of China(No.U21A20416,82020108030 to H.M.L,82103997 to B.W.);the China Postdoctoral Science Foundation(No.2021M692950 to B.W.,2021M702942 to L.J.Z.).
Post-translational modifications(PTMs)of proteins play a crucial role in living organisms,altering the properties and functions of proteins.There are over 450 known PTMs involved in various life activities.LSD1(lysine...
关键词：Enzyme activity Histone demethylase Human diseases LSD1 POST-TRANSLATIONAL 
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