噬菌体在食品应用中的安全性  

The Safety of Bacteriophage in Food Applications

作　　者：丛聪 袁玉玉 王丽丽[1,2,4] 李晓宇[1,2,4] 李淑英 徐永平[1,2,3,4] Cong Cong;Yuan Yu-yu;Wang Li-li;Li Xiao-yu;Li Shu-ying;Xu Yong-ping(School of Bioengineering,Dalian University of Technology,Dalian 116024;Center for Food Safety of Animal Origin,Ministry of Education,Dalian 116600;Dalian SEM Bio-Engineering Technology Co.Ltd,Dalian 116620;Center for Phage Applied Engineering Technology of Dalian SEM,Liaoning Province,Dalian 116600)

机构地区：[1]大连理工大学生物工程学院,辽宁大连116024 [2]动物性食品安全保障技术教育部工程研究中心,辽宁大连116600 [3]大连赛姆生物工程技术公司,辽宁大连116620 [4]辽宁省大连赛姆噬菌体应用工程技术研究中心,辽宁大连116600

出　　处：《国外医药（抗生素分册）》2019年第5期410-419,共10页World Notes on Antibiotics

基　　金：国家海洋公益项目(201405003-3)

摘　　要：近几年来,经食物传播的细菌性感染疾病处于增多的趋势,各国早已开始密切关注食品安全的问题。噬菌体是细菌的天敌,在很早之前已被人们用来治疗各种细菌性疾病,近几十年来噬菌体在食品工业上的应用也显示出广阔的前景,尤其是在即食食品领域可作为食品添加剂来杀灭食源性致病菌。噬菌体本身具有的宿主特异性特点也说明它是保障食品安全的理想工具。但消费者心中依旧存在很多顾虑和排斥,噬菌体本身是否会对人体有害?噬菌体具有哪些潜在的风险?……为了消除大众对于噬菌体的误解,本文旨在探讨噬菌体自身安全性的问题,并对噬菌体在食品工业中的应用前景进行探讨。In recent years,the spread of foodborne bacterial infections is on the rise.The world has started to pay close attention to food safety issues.Bacteriophages are natural enemies of bacteria and have long been used by people to treat various bacterial diseases.Bacteriophages also have great promise in the food industry,especially in the field of ready-to-eat foods can be used as food additives to kill food-borne pathogens.Host-specific phages themselves also show that they’re the ideal tools to ensure food safety.However,many consumers still have some apprehension and rejection in their minds.Do bacteriophages themselves are harmful to human beings?What are the potential risks of phages?...In order to eliminate the public’s misunderstanding of bacteriophages,this paper aims to explore the issues of bacteriophages self-safety and to explore the prospects of phages in the food industry.

关 键 词：噬菌体 食源性致病菌 安全性 食品 

分 类 号：R978.19[医药卫生—药品]