激光诱导碳纳米笼对细菌的杀伤作用  

Killing bacteria effect of graphic carbon nanocages under laser irradiation

作　　者：韩春哲 郭昱良 陈杨 桂馨[1] HAN Chunzhe;GUO Yuliang;CHEN Yang;GUI Xin(School of Life Science and Technology,Tongji University,Shanghai 200092,China)

机构地区：[1]同济大学生命科学与技术学院

出　　处：《上海大学学报（自然科学版）》2019年第4期597-603,共7页Journal of Shanghai University:Natural Science Edition

基　　金：国家自然科学基金资助项目(31370961)

摘　　要：以羰基铁为前驱体合成了由石墨壳层构成的石墨化碳纳米笼(graphic carbon nanocages,GCNCs).在671nm激光照射下,该GCNCs迅速将光能转化为热能.0.1mg/mL的GCNCs在低功率密度的671nm激光照射15 min的情况下,可将大肠杆菌杀灭,而单独激光照射不会影响细菌活性.由于GCNCs的内部空腔可装载药物,因此在多模式杀菌领域,GCNCs将会是一种性能优异的新型载体.Graphic carbon nanocages(GCNCs)are composed of graphite shells synthesized from carbonyl iron as precursors.The GCNCs could rapidly convert laser light energy to heat under 671 nm laser irradiation.E.coli incubated with 0.1 mg/mL of GCNCs were completely killed after 15 min of 671 nm laser irradiation,while the growth of E.coli was not affected by the GCNCs without laser irradiation.As GCNCs have huge internal cavity for loading drugs,these nanomaterials may be excellent carriers for multimodal bacteria killing.

关 键 词：碳纳米笼 光热转化 杀菌 

分 类 号：Q503[生物学—生物化学]