甲基丙二酸血症的神经影像学研究进展  

Advances in neuroimaging research of methylmalonic academia

作　　者：郭斌[1] 杨林峰 曹维金(综述) 郭凌飞(审校)[2] GUO Bin;YANG Linfeng;CAO Weijin;GUO Lingfei(Department of Medical Imaging,Jinan Maternal And Child Health Hospital,Jinan 250001,P.R.China;Shandong Medial Imaging Research Institate,Jinan 250021,P.R.China)

机构地区：[1]山东省济南市妇幼保健院放射科,山东济南250001 [2]山东大学附属山东省医学影像学研究所,山东济南250021

出　　处：《医学影像学杂志》2019年第9期1575-1577,共3页Journal of Medical Imaging

基　　金：山东省医药卫生科技发展计划项目(编号:2016WS0529)

摘　　要：甲基丙二酸血症是一种先天性有机酸代谢异常性疾病,是影响新生儿或婴幼儿生存率和生活质量的重要因素之一,早期发现、早期诊断显得尤为重要。中枢神经系统影像学检查在甲基丙二酸血症的诊断、预后中都具有重要的临床意义。本文主要就甲基丙二酸血症的病因、发病机制,尤其是中枢神经影像学研究进展做如下综述。Methylmalonic acidemia,a kind of congenital organic acid metabolism abnormal disease,is one of the important factors affecting the survival rate and quality of life of newborns or infants,early detection,early diagnosis is particularly important.Imaging examination of the central nervous system has important clinical significance in the diagnosis and prognosis of methylmalonic academia.In this paper,the etiology and pathogenesis of methylmalonic acidemia,especially the progress of central nervous imaging,are reviewed as follows.

关 键 词：甲基丙二酸血症 同型半胱氨酸血症 神经影像学 磁共振成像 

分 类 号：R741[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学]