Efficacy of Carboprost Tromethamine Combined with Mifepristone in the Treatment of Uterine Fibroids  

作　　者：Jun Wang Xian Zhang 

机构地区：[1]Zhucheng People’s Hospital,Zhucheng City,Weifang City,Shandong Province

出　　处：《Journal of Clinical and Nursing Research》2019年第1期3-6,共4页临床护理研究（英文）

摘　　要：The objective of this study was to investigate the clinical efficacy of carboprost tromethamine combined with mifepristone in the treatment of uterine fibroids.A total of 66 patients with uterine fibroids admitted to our hospital between April 2018 and January 2019 were selected as subjects.According to the two different treatment methods,patients were divided equally:The observation group and the control group,each group of 33 people.The oxytocin drug treatment was medicated to the control group,and the prostaglandin tromethamine combined with mifepristone was medicated to the observation group.The treatment effect,adverse reaction,operation,and uterine muscle before and after surgery were observed in these two groups:Tumor tissue progesterone receptor and estrogen receptor levels.The clinical treatment effect of the observation group was 93.94%,and the clinical treatment effect of the control group was 60.61%.The clinical treatment effect of the observation group was significantly higher than that of the control group;furthermore,the incidence of adverse reactions in the observation group in terms of rash,fatigue,nausea,and vomiting was much lower than the control group and could observe a significant difference.Finally,in observation group,the amount of intraoperative blood loss,operation time,and hospitalization time was better than those of the control group.The progesterone receptor and estrogen receptor levels in the uterine fibroid tissue after surgery should also be better than the control group,and it is worth to make a further comparison.Carboprost tromethamine combined with mifepristone is effective in the treatment of uterine fibroids and can be further developed.

关 键 词：CARBOPROST TROMETHAMINE MIFEPRISTONE UTERINE FIBROIDS clinical EFFICACY 

分 类 号：R73[医药卫生—肿瘤]