浙江常山食源性疾病病原菌分布与耐药性研究  

Pathogen distribution and drug resistance analysis of foodborn diseases in Changshan County, Zhejiang Province

作　　者：姚燕[1] 陆英[1] 张孟奇 YAO Yan;LU Ying;ZHANG Meng-qi(People's Hospital of Changshan County,Changshan,Zhejiang 324200,China)

机构地区：[1]常山县人民医院

出　　处：《中国卫生检验杂志》2019年第23期2900-2902,共3页Chinese Journal of Health Laboratory Technology

基　　金：浙江常山科技局计划项目(20150086)

摘　　要：目的调查浙江常山地区食源性疾病发生的基本情况,了解食源性疾病特定病原菌的分布和耐药性,为食源性疾病的防控、治疗提供科学参考。方法收集常山县人民医院2013年1月-2017年12月通过浙江省食源性疾病监测网审核上报的全部监测病例,采集病例生物样本开展特定病原菌检测和药敏试验,对监测数据进行描述性流行病学分析。结果共报告食源性疾病病例1 664例,采集粪便或肛拭标本1 664份,5月-10月为食源性病原菌检出高峰期,检出阳性菌株123株,检出率为7.48%。其中沙门菌构成比居首位,检出78株占63.41%,其次为副溶血性弧菌检出44株占35.78%。沙门菌对氨苄西林、环丙沙星和复方新诺明的敏感率分别为21.5%、 60.6%、 62.3%;副溶血性弧菌除对氨苄西林、头孢唑啉耐药,对其余14种抗生素有极好的敏感性,敏感率为100.0%。结论浙江省常山县食源性疾病病原菌主要为沙门菌和副溶血性弧菌,应重视加强实验室主动监测能力,根据药敏结果合理使用抗生素。Objective This study is aimed at investigating basic situations of foodborne diseases in Changshan, understanding the distribution and drug resistance of specific pathogens in foodborne diseases, and therefore providing scientific references for prevention and treatment of foodborne diseases. Methods All monitored cases reported by the People’s Hospital of Changshan County through the foodborne disease monitoring network of Zhejiang Province from January 2013 to December 2017 are firstly collected. According to this, patient’s biological samples were collected for the detection of specific pathogens and drug resistance tests, and then the monitoring data was analyzed from the perspective of descriptive epidemiology. Results A total of 1 664 cases of foodborne diseases were reported in the website and 1 664 samples of feces or anal swabs were collected. From May to October, it is a peak period for foodborn pathogen infection. 123 positive strains were detected, with a rate of 7.48%. Among them, Salmonella is the main cause, with 78 strains accounting for 63.41%, followed by Vibrio parahaemolyticus with 44 strains accounting for 35.78%. The sensitivity rates of Salmonella to ampicillin, ciprofloxacin and cotrimoxazole were 21.5%, 60.6%, and 62.3%. Apart from its resistance to ampicillin and cefazolin, Vibrio parahaemolyticus was 100.0% sensitive to the remaining 14 antibiotics. Conclusion Foodborne diseases in Changshan are mainly caused by two pathogens, namely Salmonella and Vibrio parahaemolyticus. It is necessary to strengthen the active monitoring abilities of the laboratory and rationally use antibiotics according to results of drug susceptibility.

关 键 词：食源性疾病 病原菌 耐药性 

分 类 号：R155.3[医药卫生—营养与食品卫生学]