Regional lymphadenectomy in advanced ovarian cancer: The enigma continues  

作　　者：Pankaj Kumar Garg Sandipan Chowdhury Rajkumar K Seenivasagam Dharma Ram Poonia 

机构地区：[1]Department of Surgical Oncology,All India Institute of Medical Sciences,Rishikesh,Uttarakhand 249203,India [2]Department of Obstetrics and Gynaecology,All India Institute of Medical Sciences,Rishikesh,Uttarakhand 249203,India

出　　处：《World Journal of Surgical Procedures》2020年第1期1-2,共2页世界外科手术杂志

摘　　要：The role of regional lymphadenectomy has always been a matter of discussion in the surgical management of solid tumors–Pelvic and para-aortic lymphadenectomy in ovarian cancer is one such issue.A recently published randomized trial suggested that regional lymphadenectomy in patients with advanced ovarian cancer is unlikely to offer a survival advantage.However,para-aortic and pelvic lymphadenectomy is warranted in the presence of macroscopically suspicious nodes to achieve complete cytoreduction.A longterm follow-up of the trial will demonstrate whether a prophylactic regional lymphadenectomy is associated with survival benefit in a subgroup of patients with advanced ovarian cancer who have grossly normal regional lymphnodes as evident in a widely open retroperitoneum.The role of regional lymphadenectomy has always been a matter of discussion in the surgical management of solid tumors – Pelvic and para-aortic lymphadenectomy in ovarian cancer is one such issue. A recently published randomized trial suggested that regional lymphadenectomy in patients with advanced ovarian cancer is unlikely to offer a survival advantage. However,para-aortic and pelvic lymphadenectomy is warranted in the presence of macroscopically suspicious nodes to achieve complete cytoreduction. A longterm follow-up of the trial will demonstrate whether a prophylactic regional lymphadenectomy is associated with survival benefit in a subgroup of patients with advanced ovarian cancer who have grossly normal regional lymphnodes as evident in a widely open retroperitoneum.

关 键 词：Ovarian cancer LYMPHADENECTOMY SURVIVAL RETROPERITONEUM 

分 类 号：R73[医药卫生—肿瘤]