A Review on Artificial Micro/Nanomotors for Cancer-Targeted Delivery, Diagnosis, and Therapy  

作　　者：Jiajia Wang Renfeng Dong Huiying Wu Yuepeng Cai Biye Ren 

机构地区：[1]School of Chemistry and Environment,Guangzhou Key Laboratory of Materials for Energy Conversion and Storage,Guangdong Provincial Engineering Technology Research Center for Materials for Energy Conversion and Storage,South China Normal University,Guangzhou 510006,People’s Republic of China [2]School of Materials Science and Engineering,South China University of Technology,Guangzhou 510640,People’s Republic of China

出　　处：《Nano-Micro Letters》2020年第1期124-142,共19页纳微快报（英文版）

基　　金：the Natural Science Foundation of China (Nos. 21805096 and 21671071);Natural Science Foundation of Guangdong Province (Nos. 2018A030313358 and 2017A030310432);Characteristic Innovation Projects of Guangdong Ordinary University (No. 2018KTSCX045);Applied Science and Technology Planning Project of Guangdong Province (Nos. 2015B010135009 and 2017B090917002);Innovation team project of Guangdong Ordinary University (No. 2015KCXTD005);the great scientific research project of Guangdong Ordinary University (No. 2016KZDXM023)

摘　　要：Micro/nanomotors have been extensively explored for efficient cancer diagnosis and therapy,as evidenced by significant breakthroughs in the design of micro/nanomotors-based intelligent and comprehensive biomedical platforms.Here,we demonstrate the recent advances of micro/nanomotors in the field of cancer-targeted delivery,diagnosis,and imaging-guided therapy,as well as the challenges and problems faced by micro/nanomotors in clinical applications.The outlook for the future development of micro/nanomotors toward clinical applications is also discussed.We hope to highlight these new advances in micro/nanomotors in the field of cancer diagnosis and therapy,with the ultimate goal of stimulating the successful exploration of intelligent micro/nanomotors for future clinical applications.Micro/nanomotors have been extensively explored for efficient cancer diagnosis and therapy,as evidenced by significant breakthroughs in the design of micro/nanomotors-based intelligent and comprehensive biomedical platforms.Here,we demonstrate the recent advances of micro/nanomotors in the field of cancer-targeted delivery,diagnosis,and imaging-guided therapy,as well as the challenges and problems faced by micro/nanomotors in clinical applications.The outlook for the future development of micro/nanomotors toward clinical applications is also discussed.We hope to highlight these new advances in micro/nanomotors in the field of cancer diagnosis and therapy,with the ultimate goal of stimulating the successful exploration of intelligent micro/nanomotors for future clinical applications.

关 键 词：Micro/nanomotors CANCER Drug delivery DIAGNOSIS Imaging 

分 类 号：R730.5[医药卫生—肿瘤]