米根霉利用木质纤维素生产富马酸的研究进展  

Production of Fumaric Acid from Lignocellulose by Rhizopus oryzae

作　　者：李鑫[1] 勇强[1] LI Xin;YONG Qiang(College of Chemical Engineering,Nanjing Forestry University,Nanjing 210037,China)

机构地区：[1]南京林业大学化学工程学院

出　　处：《林产化学与工业》2020年第1期1-7,共7页Chemistry and Industry of Forest Products

基　　金：江苏省重点研发计划资助项目(BF2015007);青海省重点研发与转化计划项目(2016-HZ-819);江苏省高校自然科学研究重大项目(14KJA220003)

摘　　要：我国是木质纤维素资源高产国,拥有大量、价廉易得、可再生的农林废弃物资源,利用木质纤维素资源生物法生产生物基化学品,具有重要的社会效益和环境效益,以及较好的经济价值。富马酸是一种重要的平台化合物,广泛应用于材料、食品、医药、化工等领域。米根霉是主要的富马酸生产菌之一,其特点是营养需求低。本文对米根霉利用木质纤维素生产富马酸进行评述,详细讨论米根霉的葡萄糖和木糖代谢途径、木质纤维素原料、发酵方式以及多联产技术等对富马酸生产的影响。随着科技的进步与发展,新兴技术与手段的涌现和应用,必将有力促进米根霉利用木质纤维素工业化生产富马酸。Lignocellulosic resource,derived from agricultural and forestry residues in China,is an abundant,cheap and renewable feedstock from which can be bioconverted to bio-based chemicals such as fumaric acid.Production of bio-based chemicals from lignocellulose owes important social,environmental and economic benefits.Fumaric acid,an important platform chemical,has been widely used in the areas of materials,food,medicine,chemical engineering,etc.Rhizopus oryzae,is used as the main producer of fumaric acid and requires a little nutrients for growth.This review discussed production of fumaric acid from lignocellulose by Rhizopus oryzae,focusing on metabolic pathway of glucose and xylose,lignocellulosic feedstocks,fermentation strategies,co-production of multiple products.The emerging technologies and methods will improve large-scale production of fumaric acid from lignocellulose by Rhizopus oryzae.

关 键 词：米根霉 木质纤维素 富马酸 发酵 联产 

分 类 号：TQ35[化学工程] Q815[生物学—生物工程]