Successful treatment of systemic sclerosis complicated by ventricular tachycardia with a cardiac resynchronization therapydefibrillator:A case report  

作　　者：Yuan-Yuan Chen Hui Yan Jian-Hua Zhu 

机构地区：[1]Department of Cardiology,The First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou 310003,Zhejiang Province,China

出　　处：《World Journal of Clinical Cases》2020年第6期1129-1136,共8页世界临床病例杂志

摘　　要：BACKGROUND Systemic sclerosis is a rare connective tissue disease characterized by localized or diffuse skin thickening and fibrosis,which usually accumulates in various organs throughout the body.Tachyarrhythmia is a common clinical manifestation of cardiovascular damage in systemic sclerosis patients.However,few studies have reported the use of catheter ablation and an implantable cardioverter defibrillator in patients with systemic sclerosis complicated by ventricular tachycardia.CASE SUMMARY A 39-year woman with an 11-year history of systemic sclerosis was referred to our hospital due to three syncopal episodes in the past 6 mo.The results of an electrocardiogram and a transthoracic echocardiogram revealed ventricular tachycardia and left ventricular systolic and ventricular septum segmental motion abnormalities,respectively.The results of an electrocardiogram showed a sinus rhythm with complete blockage of the left bundle branch.In light of the progressive nature of systemic sclerosis,the presence of a left bundle branch block,and the decreased ejection fraction,a cardiac resynchronization therapydefibrillator was implanted.The patient’s clinical conditions improved,and at the3-mo follow-up,the patient was free of ventricular tachycardia and all cardiac symptoms.CONCLUSION We report the first case of systemic sderosis complicated by ventricular tachycardia that was successfully treated with a cardiac resynchronization therapy-defibrillator.BACKGROUND Systemic sclerosis is a rare connective tissue disease characterized by localized ordiffuse skin thickening and fibrosis,which usually accumulates in various organsthroughout the body.Tachyarrhythmia is a common clinical manifestation ofcardiovascular damage in systemic sclerosis patients.However,few studies havereported the use of catheter ablation and an implantable cardioverter defibrillatorin patients with systemic sclerosis complicated by ventricular tachycardia.CASE SUMMARY A 39-year woman with an 11-year history of systemic sclerosis was referred toour hospital due to three syncopal episodes in the past 6 mo.The results of anelectrocardiogram and a transthoracic echocardiogram revealed ventriculartachycardia and left ventricular systolic and ventricular septum segmentalmotion abnormalities,respectively.The results of an electrocardiogram showed asinus rhythm with complete blockage of the left bundle branch.In light of theprogressive nature of systemic sclerosis,the presence of a left bundle branchblock,and the decreased ejection fraction,a cardiac resynchronization therapydefibrillatorwas implanted.The patient’s clinical conditions improved,and at the3-mo follow-up,the patient was free of ventricular tachycardia and all cardiacsymptoms.CONCLUSION We report the first case of systemic sclerosis complicated by ventriculartachycardia that was successfully treated with a cardiac resynchronizationtherapy-defibrillator.

关 键 词：SYSTEMIC SCLEROSIS VENTRICULAR TACHYCARDIA Cardiac RESYNCHRONIZATION therapy-defibrillator Case report 

分 类 号：R596[医药卫生—内科学] R541.7[医药卫生—临床医学]