Systematic Review and Meta-analysis of Tanshinone Capsule in the Treatment of Polycystic Ovary Syndrome  

作　　者：Bing WEI Yi ZHANG Ningning ZHAO Shiying TANG 

机构地区：[1]Institute of Traditional Chinese Medicine, Chengde Medical University/Key Laboratory of Traditional Chinese Medicine Research and Development of Hebei Province, Chengde Medical University, Chengde 067000, China

出　　处：《Medicinal Plant》2020年第2期8-12,共5页药用植物：英文版

摘　　要：[Objectives]To study the efficacy and safety of tanshinone capsule in the treatment of polycystic ovary syndrome(PCOS).[Methods]A randomized controlled trial or semi-randomized controlled trial of tanshinone capsule in the treatment of polycystic ovary syndrome was included.Two researchers screened the retrieved literature,extracted the data,assessed the risk of bias of the included literature,and then carried out meta-analysis.[Results]A total of 5 articles were included,involving 350 patients.The results of meta-analysis showed that compared with the control group,tanshinone capsule could reduce total cholesterol[MD=-0.73,95%CI(-0.86,-0.60),P<0.00001],triglyceride[MD=-0.40,95%CI(-0.57,-0.23),P<0.00001],low density lipoprotein cholesterol[MD=-0.47,95%CI(-0.73,-0.53),P<0.00001],follicle stimulating hormone[MD=-0.63,95%CI(-0.73,-0.53),P<0.00001],increase high density lipoprotein cholesterol[MD=0.28,95%CI(0.20,0.35),P<0.00001],the effective rate(P=0.06)and luteinizing hormone(P=0.07)in the treatment of polycystic ovary syndrome.[Conclusions]Tanshinone capsule could effectively improve the level of lipid metabolism and follicle stimulating hormone in patients with polycystic ovary syndrome.

关 键 词：POLYCYSTIC OVARY SYNDROME TANSHINONE CAPSULE META-ANALYSIS Systematic review 

分 类 号：R71[医药卫生—妇产科学]