成人型神经元核内包涵体病的影像学表现  

Imaging manifestations of adult-onset neuronal intranuclear inclusion disease

作　　者：陈学飞[1] 饶友鹏[1] 林攀[2] CHEN Xuefei;RAO Youpeng;LIN Pan(Division of CT/MR,Second Hospital of Longyan,Longyan 364000,China)

机构地区：[1]福建省龙岩市第二医院CT、MR室,福建龙岩364000 [2]福建省龙岩市第二医院神经内科,福建龙岩364000

出　　处：《中国中西医结合影像学杂志》2020年第3期257-259,共3页Chinese Imaging Journal of Integrated Traditional and Western Medicine

摘　　要：目的:探讨成人型神经元核内包涵体病(NIID)的影像学特征。方法:收集5例NIID的临床与影像学资料,分析其CT和MRI表现。结果:4例行CT平扫示脑白质呈低密度。4例行MRI扫描,T1WI示脑白质呈低信号,T2WI、T2 FLAIR呈高信号,DWI示皮髓质交界处(U型纤维)持续性高信号,即皮层下火焰征、尿布征;2例行增强扫描,未见明显强化。结论:NIID的影像学表现具有一定特征,掌握其影像学表现可提高对该病的诊断水平。Objective:To study imaging manifestations of adult-onset neuronal intranuclear inclusion disease(NIID)and their correlation with pathology,in order to improve the diagnostic accuracy.Methods:The clinical and imaging features of 5 cases of NIID with pathology proven were retrospectively analyzed,and the CT and MRI features were studied.Results:Low density was shown on non-enhanced CT imaging in brain white matter.Low signal on T1WI,high signal on T2WI and T2 FLAIR,and persistent high signal on DWI at the corticomedullary junction(U-shaped fibers),which called“subcortical flame sign”and“diaper sign”,with no obvious enhancement.Conclusions:NIID has certain characteristics.Grasping its imaging signs can improve the diagnostic level of the disease.

关 键 词：神经元核内包涵体病 神经变性 体层摄影术 X线计算机 磁共振成像 病理 

分 类 号：R741[医药卫生—神经病学与精神病学] R445.2[医药卫生—临床医学] R816.1