盐酸溶液中17种氨基酸混合溶液标准物质的研制  

Preparation of 17 kinds of amino acids mixed solution standard materials in hydrochloric acid solution

作　　者：贾铮[1] 周剑[1] 王敏[1] 李兰[1] 杨梦瑞[1] 徐思远[1] 田静[1] 樊霞[1] JIA Zheng;ZHOU Jian;WANG Min;LI Lan;YANG Meng-Rui;XU Si-Yuan;TIAN Jing;FAN Xia(Key Laboratory of Agricultural Product Quality and Safety Research of Ministry of Agriculture,Institute of Quality Standard and Testing Technology for Agro-Products,Chinese Academy of Agricultural Sciences,Beijing 100081,China)

机构地区：[1]中国农业科学院农业质量标准与检测技术研究所,农业农村部农产品质量安全重点实验室,北京100081

出　　处：《食品安全质量检测学报》2020年第9期2722-2732,共11页Journal of Food Safety and Quality

基　　金：“十三五”国家重点研发计划项目(2016YFF0201105);中国农业科学院创新工程。

摘　　要：目的研制盐酸溶液条件下的17种氨基酸混合溶液标准物质。方法选用17种氨基酸纯度标准物质,采用氨基酸分析仪对各种标准物质的主成分及杂质进行了准确分析,评估了组分相互干扰情况,在此基础上采用重量-容量法配制了盐酸溶液中17种氨基酸混合溶液标准物质,以配制值作为标准物质的量值,并对标准物质进行了均匀性、稳定性检验和不确定度评估。结果结果表明,制备的混合溶液标准物质均匀性、稳定性良好,不确定度评估合理,满足国家标准物质技术要求,研制的2个不同浓度的混合溶液标准物质均已通过标准物质评审并获批。结论该类标准物质的研制对于保证农产品及其投入品中氨基酸成分检测以及实验室质量控制等具有重要意义。Objective To develop the standard substance of 17 amino acids mixed solution under the condition of hydrochloric acid solution.Methods The main components and residues in 17 amino acid standard material was evaluated with amino acid analyzer.The interactive interruption among components was evaluated,based on which a mixture of 17 amino acid standard material in hydrochloride was made according to weight-volume method.Based on the measured value of standard material,the evenness,stability,and uncertainty of standard material was evaluated.Results The results showed that the mixture solution of standard material had good uniformity,stability,and reasonable uncertainty,which complied the requirement by the national standard material.Both mixture of standard material were approved by the evaluation committee.Conclusion The development of standard material is of significant importance to ensure the accuracy of amino acid measurement in agro-products and agricultural inputs,and the quality control in laboratory.

关 键 词：氨基酸 盐酸溶液 混合溶液 标准物质 

分 类 号：TQ421.31[化学工程] O629.71[理学—有机化学]