遗传性大肠癌患者亲属生活质量现状及影响因素分析  

Current status and influencing factors of quality of life among relatives of patients with hereditary colorectal cancer

作　　者：肖方 蒋超南[2] 王叶[3] 吴晓丹[4] Xiao Fang;Jiang Chaonan;Wang Ye;Wu Xiaodan(Stomach Surgery,Sun Yat-sen University Cancer Center,Guangzhou 510060,China;Department of Gynecology,Sun Yat-sen University Cancer Center,Guangzhou 510060,China;Department of Hematology,Sun Yat-sen University Cancer Center,Guangzhou 510060,China;Colorectal Department,Sun Yat-sen University Cancer Center,Guangzhou 510060,China)

机构地区：[1]中山大学肿瘤防治中心胃外科,广州510060 [2]中山大学肿瘤防治中心妇科,广州510060 [3]中山大学肿瘤防治中心血液科,广州510060 [4]中山大学肿瘤防治中心结直肠科,广州510060

出　　处：《中华现代护理杂志》2020年第21期2862-2866,共5页Chinese Journal of Modern Nursing

基　　金：国家重点研发计划资助-NCRCC(2017YFC0908202);广东省医学科研基金(A2019004)。

摘　　要：目的探讨遗传性大肠癌患者亲属的生活质量现状并探讨其影响因素。方法采用便利抽样法,选取2016年12月—2018年5月在广州市某三级甲等医院结直肠科住院的遗传性大肠癌患者血亲亲属照顾者278名作为研究对象。采用自编的一般资料调查表和世界卫生组织生存质量测定量表简表(WHOQOL-BREF)对其进行调查。共发放问卷278份,回收274份,有效问卷274份。结果274名遗传性大肠癌患者血亲亲属的生活质量得分为(83.49±11.88)分。多重线性回归分析结果显示,家庭人均月收入、是否有慢性病、婚姻状况、血亲亲属中肿瘤患者人数是遗传性大肠癌患者血亲亲属生活质量的影响因素(P<0.05)。结论遗传性大肠癌患者亲属生活质量有待提高,医护人员应关注家庭收入较低、有慢性病、未婚及家族中患癌人数较多的遗传性大肠癌患者血亲亲属,并采取针对性的护理措施改善大肠癌遗传性亲属的生活质量。Objective To explore the current status and influencing factors of quality of life among relatives of patients with hereditary colorectal cancer.Methods From December 2016 to May 2018,we selected 278 blood relative caregivers of inpatients with hereditary colorectal cancer of Colorectal Department at a ClassⅢGrade A hospital in Guangzhou as the research objects by convenience sampling.All caregivers were investigated with the self-designed General Information Questionnaire and the World Health Organization Quality of Life-BREF(WHOQOL-BREF).A total of 278 questionnaires were distributed,274 were recovered and 274 were valid.Results Among 274 blood relatives of patients with hereditary colorectal cancer,the score of quality of life(QOL)was(83.49±11.88).Multiple linear regression analysis showed that the influencing factors of QOL of blood relatives of patients with hereditary colorectal cancer included the family monthly income per person,chronic diseases,marital status and number of cancer patients among blood relatives with statistical differences(P<0.05).Conclusions QOL of relatives of patients with hereditary colorectal cancer needs to be improved.Medical and nursing staff should pay attention to relatives of hereditary colorectal cancer patients with low family income,chronic diseases,unmarried and a large number of cancer patients in the family,and take target nursing intervention to improve their QOL.

关 键 词：结直肠肿瘤 遗传性 血亲亲属 生活质量 影响因素 

分 类 号：R735.34[医药卫生—肿瘤]