Single-Cell RNA Sequencing Reveals Cell-Type-Specific Mechanisms of Neurological Diseases  

作　　者：Zhen-Ge Luo Jian Peng Ting Li 

机构地区：[1]School of Life Science and Technology,ShanghaiTech University,Shanghai 200031,China [2]Institute of Neuroscience,State Key Laboratory of Neuroscience,Center for Excellence in Brain Science and Intelligence Technology,Chinese Academy of Sciences,Shanghai 200031,China [3]University of the Chinese Academy of Sciences,Beijing 100049,China

出　　处：《Neuroscience Bulletin》2020年第7期821-824,共4页神经科学通报（英文版）

基　　金：supported by Grants from the National Natural Science Foundation of China (31490591);the National Key R&D Program of China (2017YFA0700500);a Frontier Key Project of the Chinese Academy of Sciences (QYZDJ-SSWSMC025);a Shanghai Municipal Science and Technology Major Project,China (2018SHZDZX05)。

摘　　要：Single-cell transcriptomic analysis has provided an unprecedented avenue for the identification of neuronal subtypes that are affected in neurological diseases.However,this strategy is largely hindered by the difficulty of collecting fresh samples of adult human brain.Instead,postmortem brain tissue from both normal and diseased human subjects is more accessible.

关 键 词：DIFFICULTY DISEASES Type 

分 类 号：R741.02[医药卫生—神经病学与精神病学]