Multislice spiral computed tomography imaging in evaluating hemophilic arthropathy  

作　　者：Yu-Xia Zhang M ei-Xia Li Shu-Fang Wei Lu Zhang Tian-Ming Cheng Ying-Hui Ge 

机构地区：[1]Department of Medical Imaging,People's Hospital of Zhengzhou University,Henan Provincial People's Hospital,Central China Fuwai Hospital,Zhengzhou,Henan 450003,China [2]Department of Radiology,The First Affiliated Hospital of Xinxiang Medical University,Weihui,Henan 453100,China [3]Department of Medical Imaging,People's Hospital of Zhengzhou University,Henan Provincial People's Hospital,Zhengzhou,Henan 450003,China

出　　处：《Chinese Medical Journal》2020年第14期1669-1675,共7页中华医学杂志（英文版）

基　　金：This work was supported by the grants from the National Natural Science Foundation of China(No.81271543);the Medical Science and Technology Research Project of Henan Province(No.2018020470).

摘　　要：Background:Certain hemophilia patients are unable to cooperate with or afford magnetic resonance imaging(MRI)examinations.The purpose of our study was to explore the value of multislice spiral computed tomography(MSCT)in evaluating hemophilic arthropathy(HA).Methods:Thirty-eight patients with 73 joints of HA were consecutively selected from January 2016 to May 2018 for this prospective study.All 73 joints were examined by X-ray,CT,and MRI within 2 days.The MRI scores of the joints were determined by the International Prophylaxis Study Group(IPSG)standard.The CT findings were quantified according to the IPSG standard,except for cartilage injury,which was quantified by joint space narrowing using the X-ray Pettersson score.The CT and MRI scores were compared by the paired Wilcoxon signed-rank test.The correlations between the CT score of joint space narrowing and MRI score of cartilage injury and the total CT and MRI scores were analyzed by Spearman rank correlation.The kappa test was used to compare the consistency of CT and MRI scores.Results:MRI was superior to CT based on the scores for small amount of effusion(P<0.05),synovial hypertrophy and hemosiderin deposition in the mild groups(P<0.05).The CT and MRI scores were not significantly different for moderate and massive effusion,synovial hypertrophy,and hemosiderin deposition in the moderate and severe groups,bone erosion or cystic changes(P>0.05),and there was a high degree of consistency between the two scores(kappa>0.81).The consistency between the Pettersson scores of joint space narrowing on CT and the IPSG scores of cartilage injury on MRI was high(kappa=0.774,P<0.05).Conclusion:The image scores of MSCT are generally consistent with MRI except for mild synovitis,which can be used as an alternative for the evaluation of HA.

关 键 词：HEMOPHILIA ARTHRITIS Magnetic resonance imaging Computed tomography RADIOGRAPHY Comparative evaluation 

分 类 号：R554.1[医药卫生—血液循环系统疾病] R684.3[医药卫生—内科学]