N-乙酰神经氨酸对婴幼儿的营养功能及其在婴幼儿配方产品中的应用现状  

Nutritional function of N-acetylneuraminic acid on infants and its application in infant formula

作　　者：卢晓婷 刘钊燕 罗贇 梁雪 毛颖异 蔡小堃 朱惠莲[1] LU Xiao-ting;LIU Zhao-yan;LUO Yun;LIANG Xue;MAO Ying-yi;CAI Xiao-kun;ZHU Hui-lian(Department of Nutrition,School of Public Health,Sun Yat-sen University,Guangzhou,Guangdong 510080,China;不详)

机构地区：[1]中山大学公共卫生学院营养学系,广东广州510080 [2]雅培营养中国研发中心,上海200233

出　　处：《现代预防医学》2020年第16期2953-2957,共5页Modern Preventive Medicine

摘　　要：目的综述N-乙酰神经氨酸在母乳中的含量、功能及在婴幼儿配方产品中的应用,探讨在婴幼儿配方产品中添加N-乙酰神经氨酸的必要性。方法检索PubMed和中国知网(CNKI)收集文献进行综述。结果收集文献28篇。母乳N-乙酰神经氨酸的水平与泌乳期关系密切,在初乳中含量最高,对促进婴幼儿神经系统发育、增强免疫功能有重要意义。目前国内婴幼儿配方产品中尚未添加N-乙酰神经氨酸。结论 N-乙酰神经氨酸对婴幼儿有一定益处,其添加到婴幼儿配方产品中的必要性应结合国内和国际标准、母乳水平、原料来源等因素综合考虑。Objective To review the content and functions of N-acetylneuraminic acid(Neu5 Ac)in breast milk and its applications in infant formula products,and to explore whether the supplementations of infant formula with Neu5 Ac is necessary.Methods PubMed and China National Knowledge Infrastructure(CNKI)were searched to collect relevant literatures.Results 28 studies were collected.The level of Neu5 Ac in breast milk was closely associated with the lactation period,and the highest level was in colostrum,which was significant for the development of the infant nervous and immune system.Neu5 Ac has not been added into infant formula products in China at present.Conclusion Neu5 Ac has some beneficial effects for infants.The necessity of Neu5 Ac supplementation should be considered in combination with the content of Neu5 Ac in breast milk,relative standards,the source of the materials and other factors.

关 键 词：N-乙酰神经氨酸 母乳 婴幼儿 婴幼儿配方食品 

分 类 号：R153.3[医药卫生—营养与食品卫生学]