单脐动脉缺失侧别与胎儿先天性畸形的相关性分析  

Analysis of the Correlation between Laterality of Absent Umbilical Artery and Fetal Congenital Malformations

作　　者：李巧荣 龙湘党[1] 姚穗[2] 王莉萍 申建华[1] 向力群[1] 钟昕 曾璇 LI Qiao-rong;LONG Xiang-dang;YAO Sui;WANG Li-ping;SHEN Jian-hua;XIANG Li-qun;ZHONG Xin;ZENG Xuan(Medical Ultrasound Department,The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People′s Hospital,Changsha 410005,China;Obstetrics Department,The First Affiliated Hospital of Hunan Normal University/Hunan Provincial People′s Hospital,Changsha 410005,China;Special Clinic Department,The Hospital of Trade-Business in Hunan Province,Changsha 410000,China)

机构地区：[1]湖南师范大学附属第一医院(湖南省人民医院)超声医学科,长沙410005 [2]湖南师范大学附属第一医院(湖南省人民医院)产科,长沙410005 [3]湖南省财贸医院特诊科

出　　处：《国际妇产科学杂志》2020年第4期402-404,I0001,共4页Journal of International Obstetrics and Gynecology

基　　金：湖南省卫生计生委科研计划课题项目(A2017004);湖南省科技计划项目(2015SK2019)。

摘　　要：目的:探讨单胎妊娠的单脐动脉(SUA)缺失侧别发生率及其与胎儿各系统畸形发生的相关性。方法:回顾性分析130例经产后病理证实为SUA的单胎妊娠孕妇资料,按产前超声检查结果分为左位缺失组和右位缺失组,对2组不同系统畸形发生率进行比较。结果:单胎妊娠SUA发生率0.59%(130/22055)。130例SUA中,单纯性SUA发生率为70%(91/130),非单纯性SUA发生率为30%(39/130),其中合并心血管畸形30例(30/130,23.1%)最常见。130例SUA中,左位缺失82例(63.1%),右位缺失48例(36.9%);左位缺失组合并多发畸形和复杂性心血管畸形的发生率明显高于右位缺失组(24.4%vs.8.3%,P=0.023;23.2%vs.6.3%,P=0.013)。结论:在单胎妊娠的SUA胎儿中,左位缺失者更常见,且更易合并多发畸形及复杂性心血管畸形。Objective:To explore the proportion of the absence of umbilical artery(AUA)in singleton pregnancy and its correlation with the fetal malformations of various systems.Methods:Data of 130 cases of singleton pregnancies confirmed as single umbilical artery(SUA)by postpartum pathology were retrospectively analyzed.According to the results of prenatal ultrasound examination,they were divided into the left AUA group and the right AUA group,and the incidence of malformations of different systems between the two groups was compared.Results:The incidence of SUA in singleton pregnancy was 0.59%(130/22055).Among the 130 cases of SUA,the incidence of isolated SUA was 70%(91/130)and the incidence of non-isolated SUA was 30%(39/130).Among them,30 cases(30/130,23.1%)complicated with cardiovascular malformations were the most common.Among the 130 cases of SUA,there were 82 cases of left AUA and 48 cases of right AUA(63.1%vs.36.9%);The incidence of multiple malformations and complex cardiovascular malformations in the left AUA group was significantly higher than that in the right AUA group(24.4%vs.8.3%,P=0.023;23.2%vs.6.3%,P=0.013).Conclusions:In singleton pregnancy with SUA fetus,the left AUA is more common,and it is more likely to be associated with multiple malformations and complex cardiovascular malformations.

关 键 词：单脐动脉 孕妇 脐动脉 产前诊断 超声检查 产前 先天畸形 

分 类 号：R714.5[医药卫生—妇产科学]