介入放射工作人员血液指标调查分析  

Analysis of some blood indexes of interventional radiation workers

作　　者：刘涵笑 邓大平[1] 李洁清[1] 方连英 毛雪松[1] 李卫国[1] 马娅[1] 侯殿俊[1] 朱伟[1] 乔建维[1] 贾喜明[1] LIU Hanxiao;DENG Daping;LI Jieqing;FANG Lianying;MAO Xuesong;LI Weiguo;MA Ya;HOU Dianjun;ZHU Wei;QIAO Jianwei;JIA Ximing(Institute of Radiation Medicine Shandong Academy of Medical Sciences,Shandong First Medical University&Shandong Academy of Medical Sciences,Jinan 250062 China;Shandong First Medical University&Shandong Academy of Medical Sciences)

机构地区：[1]山东省医学科学院放射医学研究所,山东第一医科大学(山东省医学科学院),山东济南250062 [2]山东第一医科大学(山东省医学科学院)

出　　处：《中国辐射卫生》2020年第3期211-214,共4页Chinese Journal of Radiological Health

基　　金：山东省自然科学基金项目(ZR2017YL007);山东省医药卫生科技发展计划项目(2016WS0520)。

摘　　要：目的了解介入放射工作人员健康状况,及时发现健康损害,防止职业性放射性疾病的发生和发展。方法选择山东省5所医院的介入放射工作人员156名为介入组,介入组根据工龄分为≤10、10~20、≥20年3个组,选择非放射工作人员134名为对照组,比较对照组和介入组及不同工龄组外周血淋巴细胞染色体畸变率、抗氧化功能和外周血细胞检测结果。结果介入组染色体畸变率高于对照组,差异具有统计学意义(P<0.05);不同工龄组染色体畸变率随工龄的增加逐渐升高,且差异具有统计学意义(P<0.05)。介入组SOD活性和GSH活性均低于对照组,且差异具有统计学意义(P<0.05),MDA含量高于对照组,但差异无统计学意义(P>0.05);不同工龄组SOD活性、GSH活性和MDA含量差异均无统计学意义(P>0.05)。介入组白细胞异常检出率和血红蛋白异常检出率均高于对照组,且差异具有统计学意义(P<0.05);不同工龄组白细胞异常检出率随工龄的增加逐渐升高,且差异具有统计学意义(P<0.05)。结论低剂量电离辐射对介入放射工作人员的血液指标产生影响,应加强介入放射的辐射防护工作,定期进行职业健康检查。Objective To understand the health status and countermeasure of interventional radiation workers in a hospital,and detect signs of health damage promptly,and prevent the occurrence and development of occupational radiation disease.Methods A total of 156 interventional radiation workers in five hospitals were selected as the intervention group.The intervention group was divided into three groups according to the working ages:≤10、10~20、≥20 years,and 134 workers who were not engaged in radiation work were selected as the control group.The chromosomal aberration(CA)rate,antioxidant function and peripheral blood cells were compared between the control group and the intervention group,different groups.Results The detection of chromosomal aberration rate in lymphocytes of intervention group was higher than that of control group,with statistically significant(P<0.05);The CA rate in lymphocytes of groups with different working ages increased with the increase of working ages,which is statistically significant(P<0.05).SOD and GSH in intervention group was lower than that of the control group,with statistically significant(P<0.05).MDA was higher than that of the control group,but there was no significant difference(P>0.05);and there was no significant difference in SOD、GSH and MDA between different working ages groups(P>0.05).The abnormal rate of WBC、HGB in intervention group was higher than that of the control group,and the abnormal rate of WBC and HGB was statistically significant(P<0.05).The abnormal rate of WBC of groups with different working ages increased with the increase of working ages and it had significant difference(P<0.05).Conclusion Low dose ionizing radiation have an impact on interventional radiologists in some blood indexes,we should strengthen the radiation protection work of intervention radiation and carry out occupational health examination regularly.

关 键 词：低剂量电离辐射 介入放射工作人员 染色体畸变 抗氧化功能 外周血细胞 

分 类 号：X591[环境科学与工程—环境工程]