核桃油中亚麻酸对小鼠血脂和肝功能的影响  

Effects of linolenic acid prepared from walnut oil on blood lipid and liver function in mice

作　　者：刘皓涵 梁琪琪 王国良 潘建龙 张润光[1] 张有林[1] LIU Haohan;LIANG Qiqi;WANG Guoliang;PAN Jianlong;ZHANG Runguang;ZHANG Youlin(College of Food Engineering and Nutritional Science,Shaanxi Normal University,Xi’an 710119,China;Ankang Yingtian Ecological Agriculture and Forestry Development Co.,Ltd.,Ankang 725000,Shaanxi,China)

机构地区：[1]陕西师范大学食品工程与营养科学学院,西安710119 [2]安康市瀛天生态农林开发有限公司,陕西安康725000

出　　处：《中国油脂》2020年第8期51-54,共4页China Oils and Fats

基　　金：陕西省重点研发计划项目(2018TSCXL-NY-06-02);陕西省农业科技驱动项目(NYKJ-2018-XA-06);中央高校基本科研业务费资助项目(GK201806002)。

摘　　要：以纯度为97.2%的冷榨核桃油亚麻酸为原料,研究其对小鼠血脂和肝功能的影响。将110只雄性昆明小鼠随机分为11组,分别灌胃核桃油、亚麻酸、花生油30 d,测定小鼠血脂和肝脏指标。结果表明:亚麻酸可降低高脂血症小鼠体重、血清总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、甘油三酯(TG)、肝脏质量和肝脏系数,可提高小鼠血液高密度脂蛋白胆固醇(HDL-C)水平。研究表明核桃油中亚麻酸防治小鼠高脂血症和动脉粥样硬化症作用显著,且优于核桃油和花生油。The effects of linolenic acid with purity of 97.2% prepared from cold-pressed walnut oil on blood lipid and liver function in mice were evaluated. 110 male kunming mice were randomly divided into eleven groups and fed with walnut oil, linolenic acid and peanut oil for 30 d,then the indexes of blood lipid and liver of mice were determined. The results showed that the linolenic acid prepared by walnut oil could reduced the body weight, serum total cholesterol(TC), low-density lipoprotein(LDL-C), triglyceride(TG), liver weight and liver coefficient, while improve the level of high-density lipoprotein(HDL-C) in blood of mice. The effect of linolenic acid prepared from walnut oil on hyperlipidemia and atherosclerosis in mice was significant,and was better than walnut oil and peanut oil.

关 键 词：核桃油 亚麻酸 血脂 肝功能 

分 类 号：TS225.1[轻工技术与工程—粮食、油脂及植物蛋白工程] TS201.4[轻工技术与工程—食品科学与工程]