植物次生代谢产物对哺乳动物生物钟的调节作用  

Roles of plant secondary metabolites in the regulation of mammalian circadian clock

作　　者：张虎 梁计陵 蒋留军 陈宁[3] ZHANG Hu;LIANG Ji-Ling;JIANG Liu-Jun;CHEN Ning(Gradute School,Wuhan Sports University,Wuhan 430079,China;North Hospital of Huashan Hospital Affiliated to Fudan University,Shanghai 200040,China;Tianjiu Research and Development Center for Exercise Nutrition and Foods,Hubei Key Laboratory of Sport Training and Monitoring,College of Health Science,Wuhan Sports University,Wuhan 430079,China)

机构地区：[1]武汉体育学院研究生院,武汉430079 [2]复旦大学附属华山医院北院,上海200040 [3]武汉体育学院健康科学学院,运动训练监控湖北省重点实验室,天久运动营养食品研发中心,武汉430079

出　　处：《生命科学》2020年第6期558-565,共8页Chinese Bulletin of Life Sciences

基　　金：国家自然科学基金面上项目(31571228);湖北省体育教育与健康促进学科群项目;湖北省高等学校优秀中青年科技创新团队项目(T201624)。

摘　　要：生物钟是生物适应地球自转而形成的内在节律,哺乳动物体内生物钟与内分泌、代谢调控以及疾病均有着紧密联系。随着人类生活和工作模式的改变,生物钟紊乱已经逐渐影响到机体健康。研究发现,饮食在为机体提供物质能量的同时,也是调节生物钟的重要途径之一,并且不同物质的摄入对生物钟的调控也存在差异。现就几种植物次生代谢产物,如白藜芦醇、茶多酚和咖啡因等对生物钟调节的研究进展进行综述。Circadian clock is an internal rhythm formed by organisms to adapt to the rotation of the earth.The mammalian circadian clock is closely related to endocrine,metabolic regulation and disease.With the change in life styles and work patterns of humans,the disordered circadian clock can affect human health step by step.Evidence has confirmed that the mammal’s diets not only provide substances and energy to the body,but also become the important ways to regulate biological clock.However,there are differences in the regulation of biological clock by the intake of different substances.This article reviews the research progress in biological clock regulation by several plant secondary metabolites,such as resveratrol,tea polyphenols,and caffeine.

关 键 词：植物次生代谢产物 生物钟 白藜芦醇 茶多酚 咖啡因 

分 类 号：Q41[生物学—生理学] Q493