肾透明细胞癌增强CT征象与临床病理相关性研究  

The correlation between enhanced CT signs and clinicopathology of renal clear cell carcinoma

作　　者：陈自南 孙云峰[1] 朱建英[1] 陈煜[2] Chen Zinan;Sun Yunfeng;Zhu Jianying;Chen Yu(Department of Radiology,the Third People's Hospital of Huzhou,Hozhou,Zhejiang 313000,China;Department of Urology,the First People's Hospital of Huzhou,Huzhou,Zhejiang 313000,China)

机构地区：[1]浙江省湖州市第三人民医院放射科,313000 [2]浙江省湖州市第一人民医院泌尿外科,313000

出　　处：《中国基层医药》2020年第20期2511-2514,共4页Chinese Journal of Primary Medicine and Pharmacy

基　　金：浙江省医药卫生科技计划一般项目(2016KYB280)。

摘　　要：目的 探讨肾透明细胞癌增强CT征象与其临床病理特征的相关性.方法 回顾性分析2015年1月至2019年1月湖州市第三人民医院行肾透明细胞癌根治术后患者33例的临床病理资料,利用Speraman相关性分析增强CT征象与病理特征的关系.结果 术后病理提示包膜侵犯17例,无包膜侵犯16例,两者在病灶直径、CT增强差值及增强率上的差异均有统计学意义[(7.74±1.85)cm比(4.15±1.41)cm,(30.19±10.00) HU比(48.25 ±24.12)HU,(70.7±22.6)%比(137.0±86.6)%,t=-6.239、2.841、3.050,P=0.000、0.008、0.005].有脉管癌栓(12例)与无脉管癌栓(21例)患者的病灶直径及增强率上的差异均有统计学意义[(7.86 ±2.35) cm比(4.93±1.79) cm,(70.0±19.9)%比(121.0±81.7)%,t=-4.025、2.074,P=0.000、0.046],而CT增强差值差异无统计学意义[(30.78±11.71)HU比(43.62±22.63) HU,t=1.823,P=0.078].Spearman相关性分析表明,CT增强差值与包膜侵犯及脉管癌栓呈中度负相关(r=-0.593、-0.540,P=0.000、0.001);病灶直径与包膜侵犯呈明显正相关(r=0.781、P=0.000).结论 肾透明细胞癌病灶直径、CT增强差值及增强率有所差异,病灶直径越大、增强差值越小意味着包膜侵犯及脉管癌栓.Objective To investigate the correlation between enhanced CT features and clinicopathological features of renal clear cell carceinoma.Methods The elinicopathological data of 33 patients with renal eclear cell carcinoma after radical operation in the Third People's Hospital of Huzhou from January 2015 to January 2019 were analyzed retrospectively.The relationship between enhanced CT signs and pathological features was analyzed by speraman correlation analysis.Results The pathological findings showed that there were 17 cases of capsule invasion and 16 cases of no capsule invasion,and there were staistically significant diferences in lesion diameter,CT enhancement diference and enhancement rate between the two groups[(7.74±1.85)cm vs.(4.15±1.41)cm,(30.19±10.00)HU vs.(48.25±24.12)HU,(70.7±22.6)%vs.(137.0±86.6)%,t=-6.239,2.841,3.050,P=0.000,0.008,0.005].There were staistically signifcant diferences in lesion diameter and enhancement rate between patients with vascular tumor thrombus(12 cases)and without vascular tumor thrombus(21 cases)[(7.86±2.35)emvs.(4.93±1.79)em,(70.0±19.9)%vs.(121.0±81.7)%,1=-4.025,2.074,P=0.000,0.046],but there was no satistically signifcant diference in CT enhancement diference[(30.78±11.71)HU vs.(43.62±22.63)HU,t=1.823,P=0.078].Spearman correlation analysis showed that there was a moderate negative correlation between CT enhancement difference and capsule invasion and vascular carcinoma thrombus(r=-0.593,-0.540,P=0.000,0.001).The diameter of the lesion was positively correlated with capsule invasion(r=0.781,P=0.000).Conclusion The diameter,CT enhancement difference and enhancement rate of renal clear cell carcinoma are different.The larger the diameter of the lesion and the smaller the enhancement difference indicate the capsule invasion and vascular carcinoma thrombus.

关 键 词：腺癌 透明细胞 肾 体层摄影术 X线计算机 图像增强 病理学 

分 类 号：R737.11[医药卫生—肿瘤] R730.44[医药卫生—临床医学]