Yang xin shi tablet enhances adaptability to exercise training by relieving statin-induced skeletal muscle injury  

作　　者：Ruo-Ming Wu Bing Jiang Hui Li Wen-Zhen Dang Cong Zhang Xiao-Zheng Zhong Yi Hong Guan Ye Xiao-Yan Shen 

机构地区：[1]Central Research Institute,Shanghai Pharmaceuticals Holding Co.,Ltd.,Shanghai 200120,China [2]Department of Pharmacology,School of Pharmacy,Fudan University,Shanghai 200120,China [3]Department of Pharmacology of Chinese Materia Medica,School of Traditional Chinese Medicine,Guangdong Pharmaceutical University,Guangzhou,Guangdong 510006,China [4]SPH Qingdao Growful Pharmaceutical Co.,Ltd.,Qingdao,Shandong 266510,China

出　　处：《Chinese Medical Journal》2020年第18期2266-2268,共3页中华医学杂志（英文版）

基　　金：supported by grants from the Science and Technology Commission of Shanghai Municipality(No.15DZ1900103 and No.15DZ1900100)。

摘　　要：To the Editor:Widely used statins lower the risk of death from cardiovascular diseases.However,statin-associated skeletal muscle complaints hinder their clinical application to some extent.Yang xin shi tablet(YXST),a traditional Chinese medicine formula,can effectively improve the clinical symptoms of patients with cardiovascular diseases when combined with conventional drugs.However,the synergistic effects of YXST combined with a statin and the potential mechanisms remain unknown.Hence,exploring the effects and mechanisms of YXST in improving statin-induced muscle injury can be beneficial for the exercise rehabilitation and prognosis of patients with cardiovascular disease.

关 键 词：CARDIOVASCULAR SKELETAL DRUGS 

分 类 号：R68[医药卫生—骨科学]