Microglia-oligodendrocyte intercellular communication: role of extracellular vesicle lipids in functional signalling  

作　　者：Alice Gualerzi Marta Lombardi Claudia Verderio 

机构地区：[1]IRCCS Fondazione Don Carlo Gnocchi,Milan,Italy [2]CNR Institute of Neuroscience,Milan,Italy

出　　处：《Neural Regeneration Research》2021年第6期1194-1195,共2页中国神经再生研究（英文版）

基　　金：supported by Italian Multiple Sclerosis Foundation(FISM)/2018/R/22(to CV).

摘　　要：The term microglia refers to the group of resident brain immune-cells that are responsible,mainly,for the immune response and the homeostasis of the brain.Unlike monocyte-derived macrophages that infiltrate the brain,microglia are longlived cells which arise exclusively from the embryonic yolk sac(Stratoulias et al.,2019).Impairment in microglia functions is at the basis for the development of multiple brain diseases,including multiple sclerosis and neurodegenerative diseases.In the last decade,the number of research articles and reviews dealing with the role of microglia in the pathogenesis of brain disorders has exponentially increased.

关 键 词：al. HOMEOSTASIS diseases 

分 类 号：R741.02[医药卫生—神经病学与精神病学]