Dopaminergic-cholinergic imbalance in movement disorders: a role for the novel striatal dopamine D2-muscarinic acetylcholine M1 receptor heteromer  

作　　者：RenéA.J.Crans Francisco Ciruela 

机构地区：[1]Laboratory of Toxicology,Department of Bioanalysis,Ghent University,Ghent,Belgium [2]Unitat de Farmacologia,Departament Patologia i Terapèutica Experimental,Facultat de Medicina i Ciències de la Salut,IDIBELL,Universitat de Barcelona,L’Hospitalet de Llobregat,Barcelona,Spain [3]Institut de Neurociències,Universitat de Barcelona,Barcelona,Spain

出　　处：《Neural Regeneration Research》2021年第7期1406-1408,共3页中国神经再生研究（英文版）

基　　金：supported by the Fonds Wetenschappelijk Onderzoek(FWOSBO, Grant number 140028);Ministerio de Ciencia, Innovación y Universidades-Agencia Estatal de Investigación/FEDER(Grant number SAF2017-87349-R);Generalitat de Catalunya(Grant numbers 2017 SGR1604 and 2017 SGR595);Fundació la Marató de TV3(grant number 20152031);supported by an FWO Travel Grant for a Long Stay Abroad(grant number V420718N);an EMBO Short-Term Fellowship(grant number 6735)。

摘　　要：The striatum is the primary input structure of the basal ganglia, which participates in motivational and goaldirected behaviors(Pisani et al., 2007).In physiological conditions, local cholinergic interneurons(ChIs) and dopaminergic afferents modulate basal ganglia output through striatal projection neurons.

关 键 词：al. DOPAMINE DOPAMINE 

分 类 号：R742.5[医药卫生—神经病学与精神病学]