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作 者:邵伟 SHAO Wei(Department of Gastroenterology,Chibi City Pufang Hospital,Chibi Hubei 437300,China)
机构地区:[1]湖北省赤壁市蒲纺医院消化内科,湖北赤壁437300
出 处:《中国继续医学教育》2020年第35期174-176,共3页China Continuing Medical Education
摘 要:目的研究乌司他丁治疗重型急性胰腺炎的疗效及其对患者血清炎症因子水平的影响。方法将本院2018年9月—2019年9月治疗的88例重型急性胰腺炎患者,按照治疗差异分为两组均44例,其中对照组采取常规治疗,研究组实施乌司他丁治疗,观察两组患者症状恢复时间、炎症因子、淀粉酶、脂肪酶情况。结果治疗前两组患者的炎症因子、淀粉酶、脂肪酶均无变化(P>0.05),治疗后研究组炎症因子优于对照组,治疗后研究组淀粉酶、脂肪酶低于对照组,研究组各项症状恢复正常时间均短于对照组,差异有统计学意义(P<0.05)。结论对于重型急性胰腺炎可实施乌司他丁治疗,临床疗效较为理想,患者炎症因子水平有效改善,淀粉酶、脂肪酶下降。Objective To study the effects of Urinastatin on serum inflammatory factors for severe acute pancreatitis patients.Methods 88 severe acute pancreatitis patients treated from September 2018 to September 2019 in the hospital were selected and assigned to two groups according to different therapies,44 cases in each group.The control group was taken the routine therapy,the study group was taken Urinastatin.The symptom relief time,inflammatory factors,amylase and lipase levels were explored.Results Before treatment,inflammatory factors,amylase and lipase levels for two groups were not significantly different(P>0.05),after treatment,inflammatory factors in the study group were better than control group,amylase and lipase levels in the study group were lower than control group,symptom relief time in the study group was shorter than control group,the difference was statistically significant(P<0.05).Conclusion Urinastatin can be used to treat severe acute pancreatitis.The clinical effect is relatively satisfactory.The level of inflammatory factors in the patient is effectively improved,amylase and lipase are decreased.
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