食源性Fe^2+/Fe^3+结合活性肽的研究进展  

Recent Progress in Fe^2+/Fe^3+Chelating Peptides Derived from Foods

作　　者：林善婷 胡晓[1] 李来好[1] 杨贤庆[1] LIN Shanting;HU Xiao;LI Laihao;YANG Xianqing(Key Laboratory of Aquatic Product Processing,Ministry of Agriculture and Rural Affairs,South China Sea Fisheries Research Institute,Chinese Academy of Fishery Sciences,Guangzhou 510300,China;Wuxi Fisheries College,Nanjing Agricultural University,Wuxi 214081,China)

机构地区：[1]中国水产科学研究院南海水产研究所,农业农村部水产品加工重点实验室,广东广州510300 [2]南京农业大学无锡渔业学院,江苏无锡214081

出　　处：《食品科学》2020年第23期329-337,共9页Food Science

基　　金：现代农业产业技术体系建设专项(CARS-46);广东省自然科学基金项目(2017A030313164);广东省基础与应用基础研究基金项目(2019A1515011588);广东省科技创新战略专项资金计划项目(2018S0044);“扬帆计划”引进创新创业团队专项(2015YT02H109);中国水产科学研究院基本科研业务费资助项目(2020TD69)。

摘　　要：铁离子是构成人体组织和维持正常生理功能所必需的微量营养元素,当体内缺乏铁离子时易导致许多营养缺乏症。Fe^2+/Fe^3+结合活性肽是一种具有结合Fe^2+/Fe^3+能力,并可与之形成可溶性结合物的肽类物质,其在生物体内可促进铁离子的吸收。本文从Fe^2+/Fe^3+结合活性肽的食物来源、制备、分离纯化、结构特征以及肽-Fe2+/3+结合物的形成、结合位点、促Fe^2+/Fe^3+吸收机制等方面进行综述,以期为Fe2+/Fe3+结合活性肽的研究及产品开发提供参考。Iron ion is a necessary micronutrient for constituting human tissues and maintaining normal physiological functions.Iron deficiency in the body is prone to cause many nutritional deficiencies.Fe^2+/Fe^3+chelating peptide is a kind of peptide that has the ability to chelate Fe^2+/Fe^3+forming a soluble conjugate,which can promote the absorption of iron in the body.This paper summarizes the food sources,preparation,separation and purification,and structural characteristics of Fe^2+/Fe^3+chelating peptides,as well as the formation and chelating sites of peptide-Fe^2+/3+complexes and the mechanism for promoting Fe^2+/Fe^3+absorption,in order to provide a theoretical basis for the research and product development of Fe2+/Fe3+chelating peptide.

关 键 词：Fe^2+/Fe^3+结合活性肽 肽-Fe^2+/3+结合物 结构特征 生物活性 吸收机制 

分 类 号：TS201.4[轻工技术与工程—食品科学]