武汉市一起毒蘑菇中毒事件现场调查和鉴定  

Investigation and identification of a mushroom poisoning in Wuhan

作　　者：颜芝闻 吴晓旻[2] 裴红兵[1] 伍雅婷[2] 李海蛟[3] YAN Zhiwen;WU Xiaomin;PEI Hongbing;WU Yating;LI Haijiao(Qingshan Center for Disease Control and Prevention,Hubei Wuhan 430080,China;Institute for Environmental Health and Food Safety,Wuhan Center for Disease Control and Prevention,Hubei Wuhan 430022,China;National Institute of Occupational Health and Poison Control,Chinese Center for Disease Control and Prevention,Beijing 100050,China)

机构地区：[1]武汉市青山区疾病预防控制中心,湖北武汉430080 [2]武汉市疾病预防控制中心环境健康与食品安全所,湖北武汉430022 [3]中国疾病预防控制中心职业卫生与中毒控制所,北京100050

出　　处：《中国食品卫生杂志》2020年第5期566-569,共4页Chinese Journal of Food Hygiene

摘　　要：目的调查分析武汉市一起毒蘑菇中毒事件的处置过程,鉴定引起中毒的毒蘑菇种类,为做好此类中毒事件的处置提供借鉴。方法收集事件病例资料,开展流行病学调查,对蘑菇样品进行形态学和分子生物学鉴定并对中毒事件进行分析。结果患者均食用自行采摘并炒制的蘑菇,食量不等。病例早期临床表现以胃肠道症状为主,后期以肝、肾和凝血功能损伤为主。经形态学和分子生物学鉴定为裂皮鹅膏菌。结论本次事件是因误食裂皮鹅膏菌引起的急性中毒。结合流行病学特点和患者临床表现,证实了通过形态学及分子生物学方法对裂皮鹅膏菌的物种鉴定具有适用性。Objective Analyzing on-site disposal process of a mushroom poisoning in Wuhan.Identifying the toxin in the mushrooms and providing references for similar poisoning incidents.Methods Epidemiological investigation,clinical treatment data and suspicious poisonous mushroom sample were collected.Mushroom sample was identified by molecular analysis.Results All patients ate different quantity of fried mushroom.The early clinical symptom were mainly gastrointestinal symptoms,and the liver,kidney and coagulopathy were damaged in the later stage.The mushroom samples were identified as Amanita rimosa.Conclusion According to epidemiological,clinical,morphological and molecular biological evidence,this incident was confirmed to be a mushroom poisoning incident caused by Amanita rimosa.

关 键 词：食物中毒 毒蘑菇 裂皮鹅膏菌 分子鉴定 

分 类 号：R155[医药卫生—营养与食品卫生学]