浅析产蛋鸡用药物零日弃蛋期的制定  

Analysis on Establishment of the Zero-Egg Withdrawal Period for Veterinary Medicine Used in Laying Hens

作　　者：徐倩[1] 杨大伟[1] 刘艳华[1] 梁先明[1] 董义春[1] 苏富琴[1] XU Qian;YANG Da-wei;LIU Yan-hua;LIANG Xian-ming;DONG Yi-chun;SU Fu-qin(China Institute of Veterinary Drug Control, Beijing 100081,China)

机构地区：[1]中国兽医药品监察所,北京100081

出　　处：《中国兽药杂志》2020年第12期66-70,共5页Chinese Journal of Veterinary Drug

摘　　要：概述产蛋鸡(蛋鸡、种鸡及后备母鸡)用药物弃蛋期的制定考虑因素。根据欧盟EMA发布的欧盟最大残留限量制定指南、残留消除指南以及FDA发布的食品动物用新兽药对人类食品安全性评价的一般原则,结合已经批准的部分零日弃蛋期药物,浅析弃蛋期制定的方法和一般考虑。制定产蛋鸡用药物弃蛋期需要考虑最大残留限量、ADI合理分配、鸡蛋中药物的残留消除,其中最重要的因素是ADI合理分配。To summarize the factors affecting the egg withdrawal period establishment of veterinary medicine used in laying hens(layers,breeders and pullets).The methodological principles for the risk management recommendations referred to in Article 7 of Regulation(EC)No 470/2009 and residue depletion studies which released by EU,and General Principles for Evaluating the Human Food Safety of New Animal Drugs Used in Food-Producing Animals which released by FDA are included.The methods and factors for egg withdrawal period establishment are reviewed in combination with some approved veterinary medicine with zero-egg withdrawal period.To establish egg withdrawal period should be focused on a set of studies such as maximum residue limits(MRL),ADI rational partition,and egg residue depletion study and so on.ADI rational partition is the key factor.

关 键 词：产蛋鸡用药物 最大残留限量 ADI合理分配 零日弃蛋期 

分 类 号：S859.79[农业科学—临床兽医学]