The coastal medicinal plant Vitex rotundifolia: a mini-review on its bioactive compounds and pharmacological activity  

作　　者：Nurul Husna Azizul Wan Amir Nizam Wan Ahmad Nurul Laili Rosli Muhammad Aniq Hamzah Mohd Azmi Choo En Liang Noor Wini Mazlan Suvik Assaw 

机构地区：[1]Biomedicine Program,School of Health Sciences,Universiti Sains Malaysia,Kubang Kerian 16150,Kelantan,Malaysia [2]Faculty of Science and Marine Environment,Universiti Malaysia Terengganu,Kuala Nerus 21030,Terengganu,Malaysia

出　　处：《Traditional Medicine Research》2021年第2期1-10,共10页TMR传统医学研究

基　　金：Author would like to thank School of Health Sciences,Universiti Sains Malaysia and Universiti Malaysia Terengganu for providing the facilities to support this project;This project is fully supported by Fundamental Research Grant Scheme Vot No.59479 from Ministry of Higher Education Malaysia.

摘　　要：Humans have long used natural remedies like plants and herbs to treat disease.Furthermore,research has been ongoing to find alternative pharmaceutical drugs based on traditionally used plants,as natural products show fewer side effects compared to synthetic drugs.Medicinal plants have long been targeted in drug development due to their bioactive compounds like alkaloids,flavonoids,and terpenoids.This is not only the case for terrestrial plants,but marine environments also provide a larger diversity of flora and fauna with medicinal bioactive compounds.Vitex rotundifolia,also known as Beach Vitex,is a coastal plant that has been traditionally used to treat a variety of diseases including premenstrual syndrome,headaches,migraines,colds,and eye pain.There have been many review papers on V.rotundifolia,emphasizing its taxonomy,distribution,and biological activity.Our current mini-review not only summarizes the pharmacology and bioactivity of V.rotundifolia,but it also provides new information on the main bioactive compounds of V.rotundifolia such as flavonoids,phenolic acid,and terpenes and their current pharmacological activity in vitro and in vivo research.This information can be useful for developing new pharmaceutical and nutraceutical agents to treat and manage disease.

关 键 词：Vitex rotundifolia Fructus viticis Marine plants ANTI-INFLAMMATION ANTI-NOCICEPTION ANTIOXIDANT 

分 类 号：O62[理学—有机化学]